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Aquaporins in Glandular Secretion

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Aquaporins

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1398))

Abstract

Exocrine and endocrine glands deliver their secretory product, respectively, at the surface of the target organs or within the bloodstream. The release of their products has been shown to rely on secretory mechanisms often involving aquaporins (AQPs). This chapter will provide insight into the role of AQPs in secretory glands located within the gastrointestinal tract, including salivary glands, gastric glands, duodenal Brunner’s glands, liver, gallbladder, intestinal goblets cells, and pancreas, as well and in other parts of the body, including airway submucosal glands, lacrimal glands, mammary glands, and eccrine sweat glands. The involvement of AQPs in both physiological and pathophysiological conditions will also be highlighted.

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Acknowledgments

This work was supported by and a research credit (CDR) J.0053.20 from the Fund for Scientific Research (F.R.S.-FNRS), Foundation Jaumotte-Demoulin and David & Alice Van Buuren Fund (Belgium) and by PRIN2017 “Programmi di Ricerca Scientifica di Rilevante Interesse Nazionale 2017 (grant # 2017J92TM5) by Italian MUR to G.C. We thank B. Jellouli for her secretarial assistance. Fig. 16.1 was prepared using BioRender.

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  1. Department of Biosciences, Biotechnologies and Environment, University of Bari “Aldo Moro”, Bari, Italy

    Giuseppe Calamita

  2. Laboratory of Pathophysiological and Nutritional Biochemistry, Faculty of Medicine, Université Libre de Bruxelles, Brussels, Belgium

    Christine Delporte

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  1. School of Basic Medical Sciences, Peking University, Bei**g, China

    Baoxue Yang

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Calamita, G., Delporte, C. (2023). Aquaporins in Glandular Secretion. In: Yang, B. (eds) Aquaporins. Advances in Experimental Medicine and Biology, vol 1398. Springer, Singapore. https://doi.org/10.1007/978-981-19-7415-1_16

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