Abstract
Given the rising incidence of cognitive impairment in population, especially in elderly persons with or without Neurodegenerative diseases such as Alzheimer disease. Their prevention has become one the important and urgent action of public health, which conducts to the defiance of achieving optimal control and delaying its development. There is effort to assure a quality life of these vulnerable persons by non-pharmacological strategies. Therefore, adherence to a diet to prevent the development of cognitive disorders remains a desirable and cheaper solution. The importance of the Mediterranean diet (MD) and its benefits have received special attention. The MD is characterized by an elevated consumption of plant-based foods; legumes, fruits, seeds and nuts, bread and other forms of cereals. Also contains, moderate proportion of dairy products, medium amounts of poultry and fish, and lastly, small quantities of wine and red meat. The effect of the MD in the prevention of some chronic illness has stimulated the appetite of many researchers to study this diet in the last two decades. Previous studies have shown a significant relation between the adherence to MD and cognitive functions improvement in vulnerable patients especially patients with AD. Moreover, several findings from clinical and experimental studies have revealed evidences of some benefit of the MD on cognitive functions including working memory, reasoning, delayed recall, and processing speed. The possible mechanisms of the MD might be explained by a reduction of oxidative stress by enhancing the oxidative stress enzymes and reduce the Reactive oxygen species, improved inflammation and controlling metabolic factors.
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Abdeljalil, T., Samir, B., Youssef, A. (2023). Mediterranean Diet and Neuro-Cognition: Focus on Alzheimer Disease. In: Mohamed, W., Brogazzi, N.L., Kostrzewa, R.M. (eds) Brain-Iron Cross Talk. Nutritional Neurosciences. Springer, Singapore. https://doi.org/10.1007/978-981-19-7327-7_4
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