Tunable Biopolymers

Biomedical Applications

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Handbook of Biopolymers

Abstract

Since the turn of the century, biopolymer uses in the biomedical field have seen a tremendous rise owing to their abundance, biocompatibility, efficacy, minimal immunogenicity, and biodegradability. Biopolymer-based scaffolds - 2D films, hollow fibers, hydrogels, sponge, 2D/3D Electrospun fibers, microcarrier beads are used to produce prototypes to tackle many obstacles in the fields of biotechnology, nanoscience, and in vitro investigations for TE including bone, neuron, muscle, tendon/ligament regeneration. Besides electrospinning nanofibers as well as 3D bioprinting have sparked a lot of consideration as a forthcoming scaffold for the application in the field of TE and wound dressing. Biopolymers have piqued researchers’ interest in determining the efficacy of drug delivery to a specific region employing them as a carrier. Wound healing applications are now heavily reliant on biopolymers due to their tunability aiding their employment in production of wide- range of efficient healing-enabling products ranging from woven fibers that expands on exposure to exudate to water-rich hydrogels that prevents drying of wounds. Post-surgical physiological functioning as well as progressive diseases can be monitored using biodegradable biopolymer-based biosensors. The disintegration of the employed biopolymer-based implants reduces the need for a surgical retraction of graft as well as graft rejection. There are an almost endless number of physical behaviors that can be modified for a given purpose due to the large range of biopolymers available and the ability to combine as biopolymers, some of which are discussed later in this chapter.

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Correspondence to Amee Krishnakumar .

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Krishnakumar, A., Shedaliya, U., Shah, K., Anju, T.R. (2023). Tunable Biopolymers. In: Thomas, S., AR, A., Jose Chirayil, C., Thomas, B. (eds) Handbook of Biopolymers . Springer, Singapore. https://doi.org/10.1007/978-981-19-0710-4_32

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