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Metal Coordination Nanomedicine

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Nanomedicine

Part of the book series: Micro/Nano Technologies ((MNT))

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Abstract

Metal coordination platforms (MCPs), as emerging drug delivery carriers in the field of nanomaterials, are based on the coordination of ligands with metal ions as a framework, through a simple preparation composition process, and do not affect the activity of natural ligands. MCPs can choose a series of elements to match and play a unique role. Supramolecular MCPs have special physicochemical properties which can exploit the advantages of conventional inorganic and organic materials. By adjusting the structural composition of the metal ions and binding ligands, many multifunctional theranostic nanomedicines can be designed and synthesized. More importantly, metal-ligand self-assembly utilizing multiple functional ligands can be surface-modified, drug-encapsulated, or materially modified to accommodate flexible environmental responses. Therefore, an overview of metals and ligands in the field of nanomedicine is beneficial for current research and development and provides clear directions for future study. In this chapter, progress in the preparation and application of MCPs for nanomedicine is highlighted, and the prospects and challenges of self-assembly MCPs for functional optimization and clinical translation are discussed.

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Authors and Affiliations

  1. Cancer Center and Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macau, China

    Wei Sang & Yunlu Dai

  2. MoE Frontiers Science Center for Precision Oncology, University of Macau, Macau, China

    Wei Sang & Yunlu Dai

Authors
  1. Wei Sang
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  2. Yunlu Dai
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Corresponding author

Correspondence to Yunlu Dai .

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Editors and Affiliations

  1. Medical School, Nan**g University, Nan**g, China

    Ning Gu

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Sang, W., Dai, Y. (2023). Metal Coordination Nanomedicine. In: Gu, N. (eds) Nanomedicine. Micro/Nano Technologies. Springer, Singapore. https://doi.org/10.1007/978-981-16-8984-0_33

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