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Prophylactic Cholecystectomy in Patients with Concomitant Gallstones After Removal of CBD Stones by ERCP

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Diseases of the Gallbladder

Abstract

After endoscopic removal of common bile duct stones, cholecystectomy can be considered to reduce recurrent biliary complications in patients with gallbladder (GB) stones. To date, several retrospective and prospective studies have been reported. However, these studies had limitations with different designs, small sample sizes, and short follow-up durations, and the results varied. Some recent large-scale population-based studies recommended prophylactic cholecystectomy to reduce recurrent biliary complications in patients with concomitant GB stones after endoscopic stone removal. Whether prophylactic cholecystectomy is necessary even in elderly patients with comorbid diseases is controversial. The timing of a cholecystectomy can affect the occurrence of additional biliary events during the waiting period, the development of surgical complications, and the conversion to open surgery. As the optimal timing for cholecystectomy, it is recommended to perform early cholecystectomy after endoscopic retrograde cholangiopancreatography during the same hospitalization period.

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References

  1. Boerma D, Rauws EAJ, Keulemans YCA, Janssen IMC, Bolwerk CJM, Timmer R, et al. Wait-and-see policy or laparoscopic cholecystectomy after endoscopic sphincterotomy for bile-duct stones: A randomised trial. Lancet. 2002;360:761–5.

    PubMed  Google Scholar 

  2. Lau JYW, Leow C, Fung TMK, Suen B, Yu L, Lai PBS, et al. Cholecystectomy or gallbladder in situ after endoscopic sphincterotomy and bile duct stone removal in chinese patients. Gastroenterology. 2006;130:96–103.

    PubMed  PubMed Central  Google Scholar 

  3. Cui ML, Cho JH, Kim TN. Long-term follow-up study of gallbladder in situ after endoscopic common duct stone removal in Korean patients. Surg Endosc. 2013;27:1711–6.

    PubMed  Google Scholar 

  4. Kageoka M, Watanabe F, Maruyama Y, Nagata K, Ohata A, Noda Y, et al. Long-term prognosis of patients after endoscopic sphincterotomy for choledocholithiasis. Dig Endosc. 2009;21:170–5.

    PubMed  Google Scholar 

  5. Pereira-Lima JC, Jakobs R, Winter UH, Benz C, Martin WR, Adamek HE, et al. Long-term results (7 to 10 years) of endoscopic papillotomy for choledocholithiasis. multivariate analysis of prognostic factors for the recurrence of biliary symptoms. Gastrointest Endosc. 1998;48:457–64.

    Google Scholar 

  6. Lai J, Wang H, Chang W, Chu C, Shih S, Lin S. Recurrent cholangitis after endoscopic lithotripsy of common bile duct stones with gallstones in situ: predictive factors with and without subsequent cholecystectomy. J Laparoendosc Adv Surg Tech A. 2012;22:324–9.

    PubMed  Google Scholar 

  7. Heo J, Jung MK, Cho CM. Should prophylactic cholecystectomy be performed in patients with concomitant gallstones after endoscopic sphincterotomy for bile duct stones? Surg Endosc. 2015;29:1574–9.

    PubMed  Google Scholar 

  8. Hammarstrom LE, Holmin T, Stridbeck H. Endoscopic treatment of bile duct calculi in patients with gallbladder in situ: long-term outcome and factors. Scand J Gastroenterol. 1996;31:294–301.

    CAS  PubMed  Google Scholar 

  9. Lai KH, Lin LF, Lo GH, Cheng JS, Huang RL, Lin CK, et al. Does cholecystectomy after endoscopic sphincterotomy prevent the recurrence of biliary complications? Gastrointest Endosc. 1999;49:483–7.

    CAS  PubMed  Google Scholar 

  10. Schreurs WH, Vles WJ, Stuifbergen, W. H. N. M., Oostvogel HJM. Endoscopic management of common bile duct stones leaving the gallbladder in situ. A cohort study with long-term follow-up. Dig Surg. 2004;21:60–4.

    Google Scholar 

  11. Song ME, Chung MJ, Lee DJ, Oh TG, Park JY, Bang S, et al. Cholecystectomy for prevention of recurrence after endoscopic clearance of bile duct stones in Korea. Yonsei Med J. 2016;57:132–7.

    CAS  PubMed  Google Scholar 

  12. da Costa DW, Schepers NJ, Römkens TEH, Boerma D, Bruno MJ, Bakker OJ. Endoscopic sphincterotomy and cholecystectomy in acute biliary pancreatitis. Surgeon. 2016;14:99–108.

    PubMed  Google Scholar 

  13. Bingener J, Richards ML, Schwesinger WH, Strodel WE, Sirinek KR. Laparoscopic cholecystectomy for elderly patients: gold standard for golden years? Arch Surg. 2003;138:531–6.

    PubMed  Google Scholar 

  14. Bratzler DW, Murray CK. Laparoscopic cholecystectomy in older medicare patients. J Am Geriatr Soc. 1997;45:1157–8.

    CAS  PubMed  Google Scholar 

  15. Drake BB, Arguedas MR, Kilgore ML, Hawn MT, Wilcox CM. Economical and clinical outcomes of alternative treatment strategies in the management of common bile duct stones in the elderly: wait and see or surgery? Am J Gastroenterol. 2006;101:746–52.

    PubMed  Google Scholar 

  16. Yasui T, Takahata S, Kono H, Nagayoshi Y, Mori Y, Tsutsumi K, et al. Is cholecystectomy necessary after endoscopic treatment of bile duct stones in patients older than 80 years of age? J Gastroenterol. 2012;47:65–70.

    PubMed  Google Scholar 

  17. Ando T, Tsuyuguchi T, Okugawa T, Saito M, Ishihara T, Yamaguchi T, et al. Risk factors for recurrent bile duct stones after endoscopic papillotomy. Gut. 2003;52:116–21.

    CAS  PubMed  PubMed Central  Google Scholar 

  18. Costamagna G, Tringali A, Shah SK, Mutignani M, Zuccalà G, Perri V. Long-term follow-up of patients after endoscopic sphincterotomy for choledocholithiasis, and risk factors for recurrence. Endoscopy. 2002;34:273–9.

    CAS  PubMed  Google Scholar 

  19. Tanaka M, Takahata S, Konomi H, Matsunaga H, Yokohata K, Takeda T, et al. Long-term consequence of endoscopic sphincterotomy for bile duct stones. Gastrointest Endosc. 1998;48:465–9.

    CAS  PubMed  Google Scholar 

  20. Sugiyama M, Atomi Y. Risk factors predictive of late complications after endoscopic sphincterotomy for bile duct stones: long-term (more than 10 years) follow-up study. Am J Gastroenterol. 2002;97:2763–7.

    PubMed  Google Scholar 

  21. Prat F, Malak NA, Pelletier G, Buffet C, Fritsch J, Choury AD, et al. Biliary symptoms and complications more than 8 years after endoscopic sphincterotomy for choledocholithiasis. Gastroenterology. 1996;110:894–9.

    CAS  Google Scholar 

  22. Cheon YK, Lehman GA. Identification of risk factors for stone recurrence after endoscopic treatment of bile duct stones. Eur J Gastroenterol Hepatol. 2006;18:461–4.

    PubMed  Google Scholar 

  23. Kim DI, Kim MH, Lee SK, Seo DW, Choi WB, Lee SS, et al. Risk factors for recurrence of primary bile duct stones after endoscopic biliary sphincterotomy. Gastrointest Endosc. 2001;54:42–8.

    CAS  PubMed  Google Scholar 

  24. Jakobs R, Hartmann D, Kudis V, Eickhoff A, Schilling D, Weickert U, et al. Risk factors for symptomatic stone recurrence after transpapillary laser lithotripsy for difficult bile duct stones using a laser with a stone recognition system. Eur J Gastroenterol Hepatol. 2006;18:469–73.

    PubMed  Google Scholar 

  25. Keizman D, Ish Shalom M, Konikoff FM. Recurrent symptomatic common bile duct stones after endoscopic stone extraction in elderly patients. Gastrointest Endosc. 2006;64:60–5.

    PubMed  Google Scholar 

  26. Bergman JJ, van der Mey S, Rauws EA, Tijssen JG, Gouma DJ, Tytgat GN, et al. Long-term follow-up after endoscopic sphincterotomy for bile duct stones in patients younger than 60 years of age. Gastrointest Endosc. 1996;44:643–9.

    CAS  PubMed  Google Scholar 

  27. Kim KY, Han J, Kim HG, Kim BS, Jung JT, Kwon JG, et al. Late complications and stone recurrence rates after bile duct stone removal by endoscopic sphincterotomy and large balloon dilation are similar to those after endoscopic sphincterotomy alone. Clin Endosc. 2013;46:637–42.

    PubMed  PubMed Central  Google Scholar 

  28. Park BK, Seo JH, Jeon HH, Choi JW, Won SY, Cho YS, et al. A nationwide population-based study of common bile duct stone recurrence after endoscopic stone removal in Korea. J Gastroenterol. 2018;53:670–8.

    PubMed  Google Scholar 

  29. Lee JK, Ryu JK, Park JK, Yoon WJ, Lee SH, Lee KH, et al. Risk factors of acute cholecystitis after endoscopic common bile duct stone removal. World J Gastroenterol. 2006;12:956–60.

    PubMed  PubMed Central  Google Scholar 

  30. Frossard JL, Hadengue A, Amouyal G, Choury A, Marty O, Giostra E, et al. Choledocholithiasis: a prospective study of spontaneous common bile duct stone migration. Gastrointest Endosc. 2000;51:175–9.

    CAS  PubMed  Google Scholar 

  31. Khan MA, Khan Z, Tombazzi CR, Gadiparthi C, Lee W, Wilcox CM. Role of cholecystectomy after endoscopic sphincterotomy in the management of choledocholithiasis in high-risk patients: a systematic review and meta-analysis. J Clin Gastroenterol. 2018;52:579–89.

    PubMed  Google Scholar 

  32. Huang RJ, Barakat MT, Girotra M, Banerjee S. Practice patterns for cholecystectomy after endoscopic retrograde cholangiopancreatography for patients with choledocholithiasis. Gastroenterology. 2017;153:762–71.

    PubMed  PubMed Central  Google Scholar 

  33. Loozen CS, van Ramshorst B, van Santvoort HC, Boerma D. Early cholecystectomy for acute cholecystitis in the elderly population: a systematic review and meta-analysis. Dig Surg. 2017;34:371–9.

    PubMed  Google Scholar 

  34. Cao AM, Eslick GD, Cox MR. Early cholecystectomy is superior to delayed cholecystectomy for acute cholecystitis: a meta-analysis. J Gastrointest Surg. 2015;19:848–57.

    PubMed  Google Scholar 

  35. Iso H, Date C, Noda H, Yoshimura T, Tamakoshi A. Frequency of food intake and estimated nutrient intake among men and women: the JACC study. J Epidemiol. 2005;15(Suppl 1):S24–42.

    PubMed  Google Scholar 

  36. Young S, Peng Y, Lin X, Chen Y, Luo J, Wang Y, et al. Cholecystectomy reduces recurrent pancreatitis and improves survival after endoscopic sphincterotomy. J Gastrointest Surg. 2017;21:294–301.

    PubMed  Google Scholar 

  37. Elmunzer BJ, Noureldin M, Morgan KA, Adams DB, Coté GA, Waljee AK. The impact of cholecystectomy after endoscopic sphincterotomy for complicated gallstone disease. Am J Gastroenterol. 2017;112:1596–602.

    PubMed  Google Scholar 

  38. Disario JA, Freeman ML, Bjorkman DJ, Macmathuna P, Petersen BT, Jaffe PE, et al. Endoscopic balloon dilation compared with sphincterotomy for extraction of bile duct stones. Gastroenterology. 2004;127:1291–9.

    PubMed  Google Scholar 

  39. Ersoz G, Tekesin O, Ozutemiz AO, Gunsar F. Biliary sphincterotomy plus dilation with a large balloon for bile duct stones that are difficult to extract. Gastrointest Endosc. 2003;57:156–9.

    PubMed  Google Scholar 

  40. Itoi T, Itokawa F, Sofuni A, Kurihara T, Tsuchiya T, Ishii K, et al. Endoscopic sphincterotomy combined with large balloon dilation can reduce the procedure time and fluoroscopy time for removal of large bile duct stones. Am J Gastroenterol. 2009;104:560–5.

    PubMed  Google Scholar 

  41. Natsui M, Honma T, Genda T, Nakadaira H. Effects of endoscopic papillary balloon dilation and endoscopic sphincterotomy on bacterial contamination of the biliary tract. Eur J Gastroenterol Hepatol. 2011;23:818–24.

    PubMed  Google Scholar 

  42. Yasuda I, Fujita N, Maguchi H, Hasebe O, Igarashi Y, Murakami A, et al. Long-term outcomes after endoscopic sphincterotomy versus endoscopic papillary balloon dilation for bile duct stones. Gastrointest Endosc. 2010;72:1185–91.

    PubMed  Google Scholar 

  43. Nakai Y, Isayama H, Tsu**o T, Hamada T, Kogure H, Takahara N, et al. Cholecystectomy after endoscopic papillary balloon dilation for bile duct stones reduced late biliary complications: a propensity score-based cohort analysis. Surg Endosc. 2016;30:3014–20.

    PubMed  Google Scholar 

  44. Wang C, Tsai M, Wang Y, Yang T, Chen H, Sung W, et al. Role of cholecystectomy in choledocholithiasis patients underwent endoscopic retrograde cholangiopancreatography. Sci Rep. 2019;9(1):2168. https://doi.org/10.1038/s41598-018-38428-z.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  45. Discolo A, Reiter S, French B, Hayes D, Lucas G, Tan L, et al. Outcomes following early versus delayed cholecystectomy performed for acute cholangitis. Surg Endosc. 2019. https://doi.org/10.1007/s00464-019-07095-0. (Epub ahead of print).

  46. Mador BD, Panton ONM, Hameed SM. Early versus delayed cholecystectomy following endoscopic sphincterotomy for mild biliary pancreatitis. Surg Endosc. 2014;28:3337–42.

    PubMed  Google Scholar 

  47. Li VKM, Yum JLK, Yeung YP. Optimal timing of elective laparoscopic cholecystectomy after acute cholangitis and subsequent clearance of choledocholithiasis. Am J Surg. 2010;200:483–8.

    PubMed  Google Scholar 

  48. Mador BD, Nathens AB, **ong W, Panton ONM, Hameed SM. Timing of cholecystectomy following endoscopic sphincterotomy: a population-based study. Surg Endosc. 2017;31:2977–85.

    PubMed  Google Scholar 

  49. Reinders JSK, Goud A, Timmer R, Kruyt PM, Kruijt PM, Witteman BJM, et al. Early laparoscopic cholecystectomy improves outcomes after endoscopic sphincterotomy for choledochocystolithiasis. Gastroenterology. 2010;138:2315–20.

    PubMed  Google Scholar 

  50. Severance SE, Feizpour C, Feliciano DV, Coleman J, Zarzaur BL, Rozycki GF. Timing of cholecystectomy after emergent endoscopic retrograde cholangiopancreatography for cholangitis. Am Surg. 2019;85:895–9.

    PubMed  Google Scholar 

  51. Schiphorst AHW, Besselink MGH, Boerma D, Timmer R, Wiezer MJ, van Erpecum KJ, et al. Timing of cholecystectomy after endoscopic sphincterotomy for common bile duct stones. Surg Endosc. 2008;22:2046–50.

    PubMed  Google Scholar 

  52. Gurusamy KS, Koti R, Fusai G, Davidson BR. Early versus delayed laparoscopic cholecystectomy for uncomplicated biliary colic. Cochrane Database Syst Rev. 2013;(6):CD007196. https://doi.org/10.1002/14651858.cd007196.pub3.

  53. Hasukić S, Mesić D, Dizdarević E, Keser D, Hadziselimović S, Bazardzanović M. Pulmonary function after laparoscopic and open cholecystectomy. Surg Endosc. 2002;16:163–5.

    PubMed  Google Scholar 

  54. Hendolin HI, Pääkönen ME, Alhava EM, Tarvainen R, Kemppinen T, Lahtinen P. Laparoscopic or open cholecystectomy: a prospective randomised trial to compare postoperative pain, pulmonary function, and stress response. Eur J Surg. 2000;166:394–9.

    CAS  PubMed  Google Scholar 

  55. Neugebauer E, Troidl H, Spangenberger W, Dietrich A, Lefering R. Conventional versus laparoscopic cholecystectomy and the randomized controlled trial. cholecystectomy study group. Br J Surg. 1991;78:150–4.

    Google Scholar 

  56. de Vries A, Donkervoort SC, van Geloven AAW, Pierik EGJM. Conversion rate of laparoscopic cholecystectomy after endoscopic retrograde cholangiography in the treatment of choledocholithiasis: does the time interval matter? Surg Endosc. 2005;19:996–1001.

    Google Scholar 

  57. Friis C, Rothman JP, Burcharth J, Rosenberg J. Optimal timing for laparoscopic cholecystectomy after endoscopic retrograde cholangiopancreatography: a systematic review. Scand J Surg. 2018;107:99–106.

    CAS  PubMed  Google Scholar 

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  1. Division of Gastroenterology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Yonsei University College of Medicine, Goyang-si, Gyeonggi-do, Korea

    Byung Kyu Park

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  1. Department of Internal Medicine, NHIS Ilsan Hospital, Goyang-si, Kyonggi-do, Korea (Republic of)

    Jae Bock Chung

  2. Department of Internal Medicine, Kouri Hospital, Kansai Medical University, Neyagawa, Osaka, Japan

    Kazuichi Okazaki

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Park, B.K. (2020). Prophylactic Cholecystectomy in Patients with Concomitant Gallstones After Removal of CBD Stones by ERCP. In: Chung, J., Okazaki, K. (eds) Diseases of the Gallbladder. Springer, Singapore. https://doi.org/10.1007/978-981-15-6010-1_28

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  • DOI: https://doi.org/10.1007/978-981-15-6010-1_28

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