Abstract
This research summary the trend in synthesis of Hydroxyapatite (HA) using different route such as dry method and wet method (co-precipitation method; emulsion method, hydrolysis method, sol-gel method, hydrothermal method). In addition, the research group also report the technique to synthesis nano-structure HA by hydrothermal reaction using Ca(OH)2 and H3PO4 with the Ca/P molar ratio of 1.67. The mixture after homogenized for 2 h, follow by hydrothermal reaction at different hydrothermal temperature time (100 °C, 150 °C, and 180 °C) and different hydrothermal reaction time (0 h, 12 h and 24 h). The 180 °C-hydrothermal treated-HA has needle-like shape with the diameter of 10 ~ 20 nm and length of below 100 nm, which is similar with human bone. For the hydrothermal reaction, temperature is the key to form nanostructure HA.
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Acknowledgement
This research is funded by Vietnam National University Ho Chi Minh City (VNU-HCM) under grant number B2015-20a-01. Some of the material characterization facility is supported by National key lab for Polymer and Composite Materials-HCMUT, VAST and HUFI.
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Kien, P.T., Phu, H.D., Linh, N.V.V., Quyen, T.N., Hoa, N.T. (2018). Recent Trends in Hydroxyapatite (HA) Synthesis and the Synthesis Report of Nanostructure HA by Hydrothermal Reaction. In: Chun, H., Park, K., Kim, CH., Khang, G. (eds) Novel Biomaterials for Regenerative Medicine. Advances in Experimental Medicine and Biology, vol 1077. Springer, Singapore. https://doi.org/10.1007/978-981-13-0947-2_18
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