Operating Modes, Scale-Up and Optimization of Chromatographic Processes

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Chromatographic and Membrane Processes in Biotechnology

Part of the book series: NATO ASI Series ((NSSE,volume 204))

Abstract

If you ask someone about the interest and drawbacks of chromatography, he will probably answer: “the method is very powerful, but also very expensive”. The aim of this article relies in showing how the right use of chromatography may lead to very competitive prices regarding to other techniques for a given purification

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References

  1. C.A.Cordis,Chromatographia, 24,1987

    Google Scholar 

  2. M. Verzele, C. Dewaelle, “Preparative High Performance Liquid Chromatography, A Practical Guideline”, TEC, GENT, Belgium, 1985

    Google Scholar 

  3. P.C. Wankat, “Large Scale Adsorption and Chromatography”, Vol. 1 and 2, CRC Press, Boca Raton, Fl, 1986

    Google Scholar 

  4. M. Bailly, D. Tondeur,G. Grevillot,Informations Chimie, 255 237,1984

    CAS  Google Scholar 

  5. PROCHROM, BP9, 54250 CHAMPIGNEULLES, FRANCE, General Documentations

    Google Scholar 

  6. K.I. Sakodynskii, S.A. Volkov, Y.A. Kovanko, V.Y. Zelivenskii, V.I. Reznikov, V.A. Averin, J. of Chromatogr., Ref. 13138, 1980.

    Google Scholar 

  7. M. Perrut, M. Pointet, H. Tollet De Santerre, French Patent Nr 79.10.649, April 26th, 1979.

    Google Scholar 

  8. P. Wankat, “Efficient Fractionation by Ion Exchange”, in Ion Exchange: Science and Technology, NATO ASI Series, edited by Alirio. E. Rodrigues, 1986, Martinus Nijhoff Publishers

    Google Scholar 

  9. Cs. Horvath, J. Frenz, Z El-Rassi, J. Chromatogr., 255, 273, 1983

    Article  CAS  Google Scholar 

  10. Cs. Horvath, A. Nahum, J. Frenz, J. Chromatogr., 218, 365, 1981.

    Article  CAS  Google Scholar 

  11. M. Bailly, D. Tondeur, Chem. Eng. Sci., 37, 1199, 1982

    Article  CAS  Google Scholar 

  12. C. Dewaele, M. Verzele, J. Chromatogr., 260, 13, 1983.

    Article  CAS  Google Scholar 

  13. H. Colin, P. Hilaireau, A. Olalde, Analysis, 15, n˚ 8, 1987.

    Google Scholar 

  14. M. Perrut, J.C. Trap, Analysis, 15, n˚ 8, 1987

    Google Scholar 

  15. F.R. Sugnaux, C. Djerassi, J. Chromatogr., 248, 373, 1982.

    Article  CAS  Google Scholar 

  16. P.A. Bristow, J. Chromatogr., 122, 277, 1976

    Article  CAS  Google Scholar 

  17. P. Legoff and N. Midoux, “Energetics and Cost Optimization of Preparative Chromatographic Columns“ in Percolation Processes: Theory and Applications“, edited by A.Rodrigues, The Netherlands, 1981.

    Google Scholar 

  18. I. Mazsaroff and F. Regnier, J. Liq. Chrom., 9 (1986) 2563.

    Google Scholar 

  19. W.M.Skea in “High Performance Liquid Chromatography” Ch. 12, P.R. Brown and R.A. Hartwick Eds., Wiley, New York, 1989

    Chapter  Google Scholar 

  20. H. Colin, G.E.N., 22 (1988) July

    Google Scholar 

  21. G. Cretier, These de Doctorat, Universite Claude Bernard, Lyon 1, 1985

    Google Scholar 

  22. J.R.Conder and M.K.Shingary, J. Chromatogr. Sci, 11, (1973), 525

    CAS  Google Scholar 

  23. A.W.J. DE Jong,H. Poppe and J.C. Kraak, J. Chromatogr., 148, (1978), 127

    Article  Google Scholar 

  24. K.P. Hupe and H.H. Lauer, J. Chromatogr., 203, (1981), 41

    Article  CAS  Google Scholar 

  25. M. Perrut and J.C. Trap, Analysis, 1987, 15, N˚ 8

    Google Scholar 

  26. A. Jaulmes, C. Vidal-Madjar, H. Colin and G. Guiochon, J. Phys. Chem., 90 (1986) 207

    Article  CAS  Google Scholar 

  27. P.C. Haarhoff,H.J.Van Der Linde, Anal. Chem., 38, (1966), 573

    Article  CAS  Google Scholar 

  28. G. Houghton, J. Phys. Chem., 67, (1963), 84

    Article  CAS  Google Scholar 

  29. H. Brusset,D. Depeyre and J.P. Petit, Chromatographia, 11, (1978), 287

    Article  CAS  Google Scholar 

  30. J.L. Wade, A.F. Bergold,P.W. Carr, Anal. Chem., 1987, 59, 1286–1295

    CAS  Google Scholar 

  31. F. Helfferich and G.Klein, Multicomponent Chromatography, Marcel Deckker, Inc., New-York, 1970

    Google Scholar 

  32. R. M. Nicoud and D. Schweich, Journal de chimie Physique, 1988, 85 N˚ 2, 239

    Google Scholar 

  33. S. Golshan-Shirazi and G. GuiochonAnal. Chem, 60 (1988) 2364

    Article  CAS  Google Scholar 

  34. S.Golshan-Shirazi and G.Guiochon, Anal. Chem, 60 (1988) 2634

    Article  CAS  Google Scholar 

  35. G. Guiochon and S.Ghodbane, J. Phys. Chem., 92 (1988) 36

    Article  Google Scholar 

  36. R. Rosset, M. Caude, A. Jardy, Manuel de Chromatographie en Phase Liquide, Masson, Paris, 1982

    Google Scholar 

  37. J.H. Knox and H.M.Pyper, J. Chromatogr., 363 (1986)

    Google Scholar 

  38. R.M. Nicoud, H. Colin, L.C.-G.C. International, 3, Number 2, 28, 1990

    Google Scholar 

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© 1991 Springer Science+Business Media Dordrecht

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Nicoud, R.M., Perrut, M. (1991). Operating Modes, Scale-Up and Optimization of Chromatographic Processes. In: Costa, C.A., Cabral, J.S. (eds) Chromatographic and Membrane Processes in Biotechnology. NATO ASI Series, vol 204. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-3470-5_22

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  • DOI: https://doi.org/10.1007/978-94-011-3470-5_22

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-5535-2

  • Online ISBN: 978-94-011-3470-5

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