Abstract
Interactions at cell surfaces are involved in a number of regulatory functions in living systems and therefore represent interesting drug targets such as the development of cyclic peptides and peptidomimetics of the RGD sequence [1]. Here we present two further examples diminishing a protein sequence into cyclic peptides with improved affinity, selectivity and enhanced proteolytic stability.
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Kessler, H. et al. (2001). Peptidic Inhibitors for Protein-Protein Interactions at Cell Surfaces. In: Lebl, M., Houghten, R.A. (eds) Peptides: The Wave of the Future. American Peptide Symposia, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0464-0_301
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DOI: https://doi.org/10.1007/978-94-010-0464-0_301
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