Abstract
Catheter-related thrombosis is one of the late complications of totally implantable venous access port. Until now, few studies have introduced the practice of totally implantable venous access port in the clinical setting. On the basis of an extensive literature review, this chapter describes the definitions of various central venous catheter-related thrombosis, thrombogenic mechanism, clinical manifestations of thrombosis, diagnosis, prevention and treatment. The different incidence, catheter inserting technique, clinical presentations and treatment between adults and children are also demonstrated. The diagram, table and photographs from clinical cases are used to directly illustrate one of the most common complication of central venous access. The summary of both basic and clinical studies may help or serve as a guidance to provide clinical care for those in need of totally implantable venous access devices.
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References
DeBona R (1999) Thrombotic complications of central venous catheters in cancer patients. Semin Thromb Hemost 25:147–155
Lokich JJ, Bothe A, Benotti P et al (1985) Complications and management of implanted venous access catheters. J Clin Oncol 3:710–717
Hoch JR (1997) Management of the complications of long-term venous access. Semin Vasc Surg 10:135–143
Martin C, Viviand X, Saux P et al (1999) Upper extremity deep vein thrombosis after central venous catheterization via the axillary vein. Crit Care Med 27:2626–2629
** a central venous catheter. J Vasc Surg 28:260–271
Ruesch S, Walder B, Tramer MR (2002) Complications of central venous catheters: Internal jugular versus subclavian access—A systematic review. Crit Care Med 30:454–460
Zhang Qinming, Jiao Lii, Zhou Hong (2009) Comparison of implantable central venous ports with catheter insertion via external jugular cut down and subclavian puncture in children: single center experience. Pediatr Surg Int 25:499–501
Horattas MC, Wright DJ, Fenton AH et al (1998) Changing concepts of deep venous thrombosis of the upper extremity-Report of series and review of the literature. Surgery 104:561–567
Brismar BO, Hardstedt C, Jacobson S (1981) Diagnosis of thrombosis by catheter phlebography after prolonged central venous catheterisation. Ann Surg 194:779–783
Pierce CM, Wade A, Mok Q (2000) Heparin-bonded central venous lines reduce thrombotic and infective complications in critically ill children. Intensive Care Med 26:967–972
De Cicco M, Matovic M, Balestrieri L et al (1997) Central venous thrombosis: An early and frequent complication in cancer patients bearing long term silastic catheter—A prospective study. Thromb Res 86:101–113
Horattas MC, Wright DJ, Fenton AH et al (1988) Changing concepts of deep venous thrombosis of the upper extremity—report of a series and review of the literature. Surgery 104:561–567
Bern HM, Lokich JJ, Wallach SR et al (1990) Very low dose of warfarin can prevent thrombosis in central venous catheters: A randomized, prospective trial. Ann Inter Med 112:423–428
Monreal M, Alastrue A, Rull M et al (1996) Upper extremity deep venous thrombosis in cancer patients with venous access devices: Prophylaxis with a low molecular weight heparin (Fragmin). Thromb Haemost 75:251–253
Massicotte P, Julian JA, Gent M et al (2003) An open-label randomized controlled trial of low molecular weight heparin for the prevention of central venous line related thrombotic complications in children: The PROTEKT study. Thromb Res 109:101–108
Reichardt P, Kretzschmar A, Biakhov M et al (2002) A phase III, randomized, double-blind, placebo-controlled study evaluating the efficacy and safety of daily low-molecular-weightheparin (dalteparin sodium) in preventing catheter-related complications (CRCs) in cancer patients with central venous catheters (CVCs). Proc Am Soc Clin Oncol 21:369a (abstr 1474)
Mismetti P, Mille D, Laporte S et al (2003) Low-molecular-weight heparin (nadroparin) and very low doses of warfarin in the prevention of upper extremity thrombosis in cancer patients with indwelling long-term central venous catheters: A pilot randomized trial. Haematologica 88:67–73
Raaf JH (1985) Results from the use of 826 vascular access devices in cancer patients. Cancer 55:1312–1321
Hurtubise MR, Bottino JC, Lawson M et al (1980) Restoring patency of occluded central venous catheters. Arch Surg 115:212–213
William DH, Robert PL (1992) Thrombosed central venous catheters: Restoring function with 6-hour urokinase infusion after failure of bolus urokinase. JPEN J Parenter Enteral Nutr 16:129–132
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Qinming, Z. (2012). Thrombosis. In: Di Carlo, I., Biffi, R. (eds) Totally Implantable Venous Access Devices. Springer, Milano. https://doi.org/10.1007/978-88-470-2373-4_23
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DOI: https://doi.org/10.1007/978-88-470-2373-4_23
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-2372-7
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