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Newest Results on the Chemistry and Pharmacology of TCM Drugs Containing Triterpene and Steroid Saponins

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Evidence and Rational Based Research on Chinese Drugs

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Abstract

The aim of this review is to provide newest results in the chemistry, pharmacology, and clinical studies of saponins-containing TCM drugs, some of them being listed in the Chinese Pharmacopoeia. It appears that literature on triterpene saponins is more abundant than that of steroid saponins, and ginseng occupies a prominent position in the list. However, other TCM drugs are well documented in recent years belonging to the genera Astragalus, Gynostemma, Bupleurum, Clematis, Dipsacus, Platycodon, Gypsophila, Anemarrhena, Lonicera, Paris, Dioscerea, Tribulus, and Ophiopogon. From a Pharmacological point of view, the most relevant results have been obtained with the cancer-related activity and neuroprotective and antidiabetic properties of saponins from Gypsophila paniculata, Dipsacus asper, and Gynostemma pentaphyllum, respectively.

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  1. Laboratoire de Pharmacognosie, EA 4267, Faculté de Pharmacie., Université de Bourgogne, Dijon, France

    Marie-Aleth Lacaille-Dubois

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  1. Center of Pharma Research, Department of Pharmacy, Ludwig-Maximillians-University, Butenandtstr. 5, Munich, 81377, Germany

    Hildebert Wagner

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    Gudrun Ulrich-Merzenich

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Lacaille-Dubois, MA. (2013). Newest Results on the Chemistry and Pharmacology of TCM Drugs Containing Triterpene and Steroid Saponins. In: Wagner, H., Ulrich-Merzenich, G. (eds) Evidence and Rational Based Research on Chinese Drugs. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0442-2_3

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