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Entdeckung von zellulären Innenstrukturen, Funktionen und Dynamik der Zelle

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Abenteuer Zellbiologie - Streifzüge durch die Geschichte

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Zusammenfassung

Die Fortentwicklung mikroskopischer Methoden dauert bis in unsere Tage an. Diese Entwicklungen waren und sind immer noch ganz entscheidend für den Fortschritt der Zellbiologie. Dies betrifft eine verbesserte Auflösung und immer anspruchsvollere Markierungsmethoden sowohl in der Licht- als auch in der Elektronenmikroskopie, die nach dem Zweiten Weltkrieg zu einem unverzichtbaren Instrument entwickelt worden war. Letztere erlaubt zwar prinzipiell eine atomare Auflösung, die jedoch ohne experimentell verstärkten Kontrast an biologischem Material wenig Sinn ergibt.  Neue lichtoptische Verfahren erlauben in vivo-Analysen und nähern sich bis auf einen Faktor ~10 der Elektronenmikroskopie.

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  1. Konstanz, Baden-Württemberg, Deutschland

    Helmut Plattner

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Plattner, H. (2021). Entdeckung von zellulären Innenstrukturen, Funktionen und Dynamik der Zelle. In: Abenteuer Zellbiologie - Streifzüge durch die Geschichte. Springer Spektrum, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-62118-9_4

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