Zusammenfassung
DNA is the abbreviation for deoxyribonucleic acid. It involves the hereditary information for humans and other organisms. The DNA is based in the cell nucleus but also in the mitochondria. The chemical bases of the DNA are adenine (A), guanine (G), cytosine (C) and thymine (T). The sequence of these bases is decisive for the makeup of organisms. The bases are connected to sugar and phosphate called nucleotide. They are formed to a spiral which is also known as double helix. The fact that DNA can replicate makes life possible. In 1869 Friedrich Miescher isolated DNA for the first time. In 1953 Francis Crick and James Watson presented their double-helix model of DNA based on an x-ray photo of Rosalind Franklin and Raymond Gosling. Francis Crick and James Watson received in 1962 the Nobel Prize in Physiology and Medicine.
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16 December 2020
Der auf S. 82 fälschlicherweise gesetzte Kommentar der Autorin „Habe ich Ihnen geschickt / Das arabische Wort für Chemie kommt hier rein“ wurde entfernt.
Bibliography
Buckley R, Morris M, Appleby J, King T, O’Sullivan D, Faxholl L (2013) The king in the park: new light on the death and burial of Richard III in the Grey Friars church, Leicester, in 1485. Antiquity 87:519–538
Burke T, Brufod MW (1987) DNA fingerprinting in birds. Nature 327:149–152
Gill P, Jeffreys AJ, Werret DJ (1985) Forensic application of DNA ‘fingerprints’. Nature 317:818–819
Gitscher J (2009) The eureka moment: an interview with Sir Alec Jeffreys. PLoS Genet 5:e100765
Hagelberg E, Gray IC, Jeffreys AJ (1991) Identification of the skeletal remains of a murder victim by DNA analysis. Nature 352:427–429
Hill AV, Jeffreys AJ (1985) Use of minisatellite DNA probes for determination of twin zygosity at birth. Lancet 2:1394–1395
Jeffreys A (2007) BBC Radio 4: Desert Island discs. http://ww.bbc.co.uk/radio4/features/desert-island-discs/castaqy/0411c084b008fcdz
Jeffreys AJ (2005) Genetic fingerprinting. Nat Med 11:1035–1039
Jeffreys AJ, Morton DB (1987) DNA fingerprinting of dogs and cats. Anim Genet 18:1–15
Jeffreys AJ, Wilson V, Then SL (1965) Hypervariable ‘minisatellite’ regions in human DNA. Nature 314:67–73
Jeffreys AJ, Brookfield JFY, Semeonoff R (1985a) Positive identification of an immigration test-case using human DNA fingerprints. Nature 317:818–819
Jeffreys AJ, Wilson V, Then SL (1985b) Individual-specific ‘fingerprints’ of human DNA. Nature 316:76–79
Jeffreys AJ, Wilson V, Kelly R, Taylor BA, Bullfield G (1987) Mouse DNA ‘fingerprints’: analysis of chromosome localization and germ-line stability of hypervariable loci in recombinant inbred strains. Nucleic Acids Res 15:2823–2836
Jeffreys AJ, Wilson V, Neumann R, Keyle J (1988) Amplification of human minisatellites by the polymerase chain reaction: towards DNA fingerprinting of single cells. Nucleic Acids Res 16:10953–10971
Jeffreys AJ, Turner M, Debenham P (1991a) The efficiency of multilocus DNA fingerprint probes for individualization and establishment of family relationships, determined from extensive casework. Am J Hum Genet 48:824–840
Jeffreys AJ, McLead A, Tamaki K, Nell DL, Monckton DG (1991b) Minisatellite repeat coding as a digital approach to DNA ty**. Nature 354:204–209
Jeffreys AJ, Allen MY, Hagelberg E, Sonnberg A (1992) Identification of the skeletal remains of Josef Megele by DNA analysis. Forensic Sci Int 56:65–76
Jeffreys AJ, Tamaki K, MacLead A, Monckton DG, Neil DL, Armour JAL (1994) Complex gene conversion events in germline mutation at human minisatellites. Nat Genet 6:136–145
Jobling MA (2013) Curiosity in the genes: the DNA fingerprinting story. https://www.investigativegenetics.com/content/4/1/20
Jobling MA, Bouzekri N, Taylor PG (1998) Hypervariable digital DNA codes for human paternal lineages: MVR-PCR at the Y-specific minisatellite, MSY1 (DYF15551). Hum Mol Genet 7:643–653
Mitchell PD, Yeh HY, Applegy J, Buckley R (2013) The intestinal parasites of King Richard III. Lancet 382:–888
Signer EH, Dubrova YE, Jeffreys AJ, Wilde C, Finch LM, Wells M, Peaker M (1996) DNA fingerprinting Dolly. Nature 394:329–330
Wetton JH, Carter RE, Parklin DT (1967) Demographic study of a wild house sparrow population by DNA fingerprinting. Nature 327:147–149
Zagorski N (2006) Profile of Alec J. Jeffreys. Proc Natl Acad Sci U S A 103:8915–8920
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Steiner, U. (2020). DNA Fingerprinting. In: Fachenglisch für BioTAs und BTAs. Springer Spektrum, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-60666-7_4
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