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Mitochondrial Genetics of the Budding Yeast Saccharomyces cerevisiae

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Genetics and Biotechnology

Part of the book series: The Mycota ((MYCOTA,volume 2))

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Abstract

Mitochondria are indispensable constituents of all eukaryotic cells. They are responsible for a series of processes such as the tricarboxylic cycle, assembly of iron-sulfur clusters and the biosynthesis of a variety of metabolites. Their most important function is the supply of energy by oxidative phosphorylation. Mitochondria are complex double membrane-bound organelles with characteristic morphology and intercellular distribution. 79 Understanding the process of mitochondrial (mt) function and inheritance is possible only by identification and characterization of the molecular components involved. This article will give an overview of mt genetics of Saccharomyces cerevisiae (S. cerevisiae.). Due to the limited space, interesting aspects of mt transport or structure and function of introns will not be reviewed. The older literature can be found in a series of reviews by Dujon (1981), Evans (1983; in which all older reviews are compiled), Wilkie (1983), Attardi and Schatz (1988), Wolf and Del Giudice (1988), Grivell (1989), Bereiter-Hahn (1990), Bereiter-Hahn and Vöth (1994), Costanzo and Fox (1990), Pon and Schatz (1991), Bolotin-Fukuhara and Grivell (1992), Piskur (1994). More recent reviews are presented by Azpiroz and Butow (1995), Grivell (1995), Yaffe (1995, 1999a,b), Warren and Wickner (1996), Hermann and Shaw (1998), Lisowsky et al. (1999), Saraste (1999), Scheffler (2000), Jensen et al. (2000), Contamine and Picard (2000), Kurland and Andersson (2000), Catlett and Weisman (2000), Boldogh et al. (2001b). It should finally be mentioned that the book, Mitochondria, by Scheffler (1999) also provides a wealth of information for mt genetics of yeast.

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  1. Institute of Biology IV (Microbiology and Genetics), Aachen Technical University, Worringer Weg, 52056, Aachen, Germany

    B. Schäfer

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  1. Fakultät für Biologie, Lehrstuhl für Allgemeine und Molekulare Botanik, Ruhr-Universität Bochum, Universitätsstraße 150, 44801, Bochum, Germany

    Ulrich Kück

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Wolf, K., Schäfer, B. (2004). Mitochondrial Genetics of the Budding Yeast Saccharomyces cerevisiae . In: Kück, U. (eds) Genetics and Biotechnology. The Mycota, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07426-8_5

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