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Regulation of Mitochondrial Gene Expression

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Biochemistry and Molecular Biology

Part of the book series: The Mycota ((MYCOTA,volume 3))

Abstract

The rudimentary genetic system of mitochondria retains only a few components of its ancestral prokaryotic genetic system. This physically and functionally distinct organellar genetic system is completely dependent upon the nucleus, since it produces only the tRNAs and rRNAs and almost none of the proteins required for a minimal protein synthesis system or for DNA replication and gene expression. The mitochondrial genome encodes mainly a few hydrophobic proteins, components of the inner mitochondrial respiratory membrane, and the genes for most other mitochondrial proteins, including the majority of the proteins required for the respiratory system, are expressed in the nucleus. Mitochondria are the outcome of one of the major steps of eukaryotic cell evolution, the result of an endosymbiosis with a member of the the α-proteobacteria.

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  1. Department of Plant Biology and Plant Molecular Genetics Institute, The University of Minnesota, 1445 Gortner Avenue, Saint Paul, Minnesota, 55108, USA

    R. Brambl

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  1. R. Brambl
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  1. Department of Plant Biology, University of Minnesota, 250 Biological Science Center, 1445 Gortner Avenue, Saint Paul, MN, 55108, USA

    Robert Brambl

  2. Department of Biochemistry, Ohio State University, 776 Biological Sciences, 484 West 12th Avenue, Columbus, OH, 43210, USA

    George A. Marzluf

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Brambl, R. (2004). Regulation of Mitochondrial Gene Expression. In: Brambl, R., Marzluf, G.A. (eds) Biochemistry and Molecular Biology. The Mycota, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-06064-3_8

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  • DOI: https://doi.org/10.1007/978-3-662-06064-3_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-07652-7

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