Abstract
To find DSMZ strains whose genomes have been sequenced and carry candidate BGCs for activation by PapR2, an advanced bioinformatic search for candidate genomes was conducted with all available genomes from the Integrated Microbial Genomes (IMG) facility of the Joint Genome Institute (JGI). BGCs that contain genes coding for SARP transcriptional regulators were identified with antiSMASH 6.0 and “relaxed” was set as strictness. The genomes were drawn from National Center for Biotechnology Information (NCBI, https://www.ncbi.nlm.nih.gov/).
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Rössler, O. (2024). Material and Methods. In: SARP-Driven Activation of Antibiotic Biosynthetic Gene Clusters in Actinomycetes. BestMasters. Springer Spektrum, Wiesbaden. https://doi.org/10.1007/978-3-658-44552-2_2
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DOI: https://doi.org/10.1007/978-3-658-44552-2_2
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