Influence of Infusion Time on the Acute Toxicity of Amphotericin B: Results of a Randomized Double-Blind Study

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Supportive Care in Cancer Patients II

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 121))

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Abstract

Despite the development of several new antifungal drugs, intravenous amphotericin B (amB) is still considered the drug of choice for the treatment of severe systemic fungal infections in immunocompromised patients. However, therapy is often limited by various side effects (Table 1). From the patients’ point of view, the acute toxic reactions (fever, chills, nausea and vomiting) induced by the drug are particularly troublesome.

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© 1991 Springer-Verlag Berlin · Heidelberg

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Arning, M., Dresen, B., Aul, C., Schneider, W. (1991). Influence of Infusion Time on the Acute Toxicity of Amphotericin B: Results of a Randomized Double-Blind Study. In: Senn, HJ., Glaus, A. (eds) Supportive Care in Cancer Patients II. Recent Results in Cancer Research, vol 121. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84138-5_41

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  • DOI: https://doi.org/10.1007/978-3-642-84138-5_41

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-84140-8

  • Online ISBN: 978-3-642-84138-5

  • eBook Packages: Springer Book Archive

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