Hemodynamic Effects of Amrinone and Changes in Norepinephrine (NE) Plasma Concentration

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Endocrinology of the Heart

Abstract

Plasma NE concentration of patients with severe heart failure (NYHA class (III-)IV) was found to be about three times higher than it was evaluated in those patients with normal hemodynamic function or mild heart failure (NYHA class I and II) [1, 2], and there is a negative correlation between circulating catecholamines and myocardial beta-receptor density [2, 3, 4]; treatment of severe heart failure with catecholamines will be rather ineffectiv.

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References

  1. Chatterjee K (1984) Angiotensin-Conversions-Enzym-Hemmer (ACE-Hemmer) bei Herzinsuffizienz. In: Sobel B, Julien D, Hugenholtz P (eds) Perspectives in Cardiology. Current Medical Literature Ltd., London, pp 178–180

    Google Scholar 

  2. Lehmann M, Rühle K, Schmid P, Klein H (1983) Hämodynamik, Plasmakatecholaminverhalten und Beta-Rezeptoren-Dichte bei Trainierten, Untrainierten und Herz-Insuffizienten. Z Kardiol 72: 529–536

    PubMed  CAS  Google Scholar 

  3. Baumann G, Riess G (1982) Verhalten kardialer Beta-Rezeptoren bei akutem Myokardinfarkt und chronischem Herzversagen. Mögliche Rolle von H2-Rezeptor-Agonisten im katecholamin-refraktären Myokard. Herz/ Kreisl 14: 169–178

    CAS  Google Scholar 

  4. Drici MD, Sbirrazzuoli V, Gibelin P, Kreitmann P, Candito P, Baudouy M, Lapolus P, Morand P (1988) Human myokardium beta adrenoreceptor regulation: relationship between density and norepinephrine Plasma Levels. Eur Heart J 9, [Suppl]: 115

    Google Scholar 

  5. Honerjäger P, Schäfer-Korting M, Reiter M (1981) Involvement of cyclic AMP in the direct inotropic action of amrinone. Naunyn Schmiedebergs Arch Pharmacol 318: 112–120

    PubMed  Google Scholar 

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© 1989 Springer-Verlag Berlin Heidelberg

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Jäger, D., Machraoui, A., Reier, W., Gude, J., Johannsen, G., Barmeyer, J. (1989). Hemodynamic Effects of Amrinone and Changes in Norepinephrine (NE) Plasma Concentration. In: Kaufmann, W., Wambach, G. (eds) Endocrinology of the Heart. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83858-3_65

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  • DOI: https://doi.org/10.1007/978-3-642-83858-3_65

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-51409-1

  • Online ISBN: 978-3-642-83858-3

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