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Radiotherapy in Childhood: Normal Tissue Injuries and Carcinogenesis

  • Chapter
Radiopathology of Organs and Tissues

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Radiotherapeutic treatment contributes to longterm survival after cancer in childhood, especially in cases of Hodgkin’s disease, acute lymphocytic leukemia (ALL), Wilms’ tumor, and soft tissue and Ewing’s sarcoma (Perez and Brady 1987; Havers 1987). Like other treatment modalities, irradiation induces early and late side-effects. In general, the early effects are reversible and the related symptoms can be treated effectively. Moreover, children often tolerate the acute local side-effects of radiotherapy better than do adults (Pizzo et al. 1985). The persistent late effects are more critical; their clinical significance is variable.

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Authors and Affiliations

  1. Radiologisches Zentrum, Universitätsklinikum Essen, Hufelandstraße 55, 4300, Essen 1, Germany

    M. Molls Priv.-Doz., Dr. med. (Oberarzt) & M. Stuschke Dr. med.

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  1. M. Molls Priv.-Doz., Dr. med.
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  2. M. Stuschke Dr. med.
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Editors and Affiliations

  1. Strahlenklinik und Poliklinik, Universitätsklinikum der Gesamthochschule Radiologisches Zentrum, Hufelandstraße 55, W-4300, Essen 1, Germany

    Eberhard Scherer

  2. Institut für Medizinische Strahlenphysik und Strahlenbiologie, Universitätsklinikum der Gesamthochschule, Hufelandstraße 55, W-4300, Essen 1, Germany

    Christian Streffer

  3. Department of Radiation Biology, The Medical College of St. Bartholomew’s Hospital, Charterhouse Square, London, EC1M 6BQ, UK

    Klaus-Rüdiger Trott

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© 1991 Springer-Verlag Berlin Heidelberg

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Molls, M., Stuschke, M. (1991). Radiotherapy in Childhood: Normal Tissue Injuries and Carcinogenesis. In: Scherer, E., Streffer, C., Trott, KR. (eds) Radiopathology of Organs and Tissues. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83416-5_16

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  • DOI: https://doi.org/10.1007/978-3-642-83416-5_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83418-9

  • Online ISBN: 978-3-642-83416-5

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