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Basic Principles in Hyperthermic Tumor Therapy

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Vascular Perfusion in Cancer Therapy

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 86))

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Abstract

The first report of heat being useful in cancer treatment is by Busch (1866), who noted the disappearance of a sarcoma after high fever caused by erysipelas. Bruns (1887) reviewed all cases of tumor regression after fever reported in literature. Coley (1893) injected patients with bacterial toxins deliberately to cause fever. There are many reports in the early 1900s of the use of applied hyperthermia in treating cancer. Interest declined during the 1930s, due in part to the advent of antibacterial agents; consequently, the number of studies diminished. There was then a period of renewed interest in hyperthermia, for example, in the possibility of combining heat with X-rays, but because heat application was technically difficult and therapeutic results of megavoltage radiotherapy by photons and electrons were excellent, hyperthermia disappeared again as a therapeutic agent.

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  1. Strahlentherapeutische Abteilung, Städtische Krankenanstalten, Kulmbacher Straße 23, 8580, Bayreuth, Germany

    F. Dietzel

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  1. F. Dietzel
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  1. Allgemeinchirurgische Klinik des Zentrums für Chirurgie, Justus-Liebig-Universität, Klinikstrasse 29, 6300, Giessen, Germany

    Konrad Schwemmle  & Karl Aigner  & 

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Dietzel, F. (1983). Basic Principles in Hyperthermic Tumor Therapy. In: Schwemmle, K., Aigner, K. (eds) Vascular Perfusion in Cancer Therapy. Recent Results in Cancer Research, vol 86. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-82025-0_31

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  • DOI: https://doi.org/10.1007/978-3-642-82025-0_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-82027-4

  • Online ISBN: 978-3-642-82025-0

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