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Particulate Suspensions as Contrast Media

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Radiocontrast Agents

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 73))

Abstract

Particulate contrast media offer exciting advantages over water-soluble media in several radiologic applications. A truly vascular contrast medium which does not diffuse into the extravascular spaces and is not hyperosmolar would be extremely useful as an intravenous angiographic medium for measuring blood flow and vascular volumes with the novel technologies such as digital fluoroscopy and dynamic computed tomography (CT) scanning. A medium which is less viscous than Ethiodol and does not embolize in the lungs would be advantageous in lymphography. The difference in impedance between solids and liquids means particulate media could potentially be useful as ultrasound contrast media (CM). Paramagnetic compounds in the form of a particulate suspension may be helpful as nuclear magnetic resonance (NMR) contrast media.

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  1. M. R. Violante
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  2. H. W. Fischer
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Editors and Affiliations

  1. School of Medicine, Department of Radiology, S-009, University of California in San Diego, La Jolla, CA, 92093, USA

    Milos Sovak

  2. Biophysica Foundation, 3333 Torrey Pines Ct., La Jolla, CA, 92037, USA

    Milos Sovak

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Violante, M.R., Fischer, H.W. (1984). Particulate Suspensions as Contrast Media. In: Sovak, M. (eds) Radiocontrast Agents. Handbook of Experimental Pharmacology, vol 73. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69515-5_14

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  • DOI: https://doi.org/10.1007/978-3-642-69515-5_14

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