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Contrast Media in Computed Tomography

  • Chapter
Radiocontrast Agents

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 73))

Abstract

Computed tomography (CT) produces remarkably accurate cross-sectional images of the human body, which are based on small differences in the X-ray attenuation among the various body tissues. The anatomic location, shape and size, homogeneity, and attenuation characteristics of structures in the body are used by the radiologist to determine their identity in the CT images. Based on this information, the radiologist attempts to determine whether a sequence of CT images represents normal anatomy or whether a pathologic lesion is present. Contrast media are routinely given to the patient prior to and during CT scanning to increase the attenuation coefficients of at least some of the tissues and organs or of their lumens. This is done to render some pathologic lesions and some normal anatomic structures more readily detectable so as to help in their differential diagnosis. This chapter will review the nature of contrast enhancement (CE) and the various applications of both conventional and experimental contrast media (CM) to computed tomography.

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Authors
  1. P. B. Dean
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  2. D. B. Plewes
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Editors and Affiliations

  1. School of Medicine, Department of Radiology, S-009, University of California in San Diego, La Jolla, CA, 92093, USA

    Milos Sovak

  2. Biophysica Foundation, 3333 Torrey Pines Ct., La Jolla, CA, 92037, USA

    Milos Sovak

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© 1984 Springer-Verlag Berlin Heidelberg

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Dean, P.B., Plewes, D.B. (1984). Contrast Media in Computed Tomography. In: Sovak, M. (eds) Radiocontrast Agents. Handbook of Experimental Pharmacology, vol 73. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69515-5_11

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  • DOI: https://doi.org/10.1007/978-3-642-69515-5_11

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