Contrast Media in Lymphography

  • Chapter
Radiocontrast Agents

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 73))

Abstract

The diagnostic potential of visualization of lymphatic vessels and lymph nodes was recognized soon after the discovery of X-rays. A variety of heavy metal salts, sodium or potassium iodides, and bromides were injected intralymphatically into cavities as well as into soft tissues. Lymphograms were produced but serious tissue damage resulted [1,2]. In 1931, it was found that Thorotrast, a thorium-containing colloid, which at the time was believed to be a biologically inert substance, would, upon injection into the pleural space of animals, visualize the thoracic and diaphragmatic lymph vessels [3]. Also, the newly discovered iodized oil, Lipiodol, instilled into the maxillary sinus, successfully demonstrated lymphatic drainage of the maxillary area [4].

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Sovak, M. (1984). Contrast Media in Lymphography. In: Sovak, M. (eds) Radiocontrast Agents. Handbook of Experimental Pharmacology, vol 73. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69515-5_10

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  • DOI: https://doi.org/10.1007/978-3-642-69515-5_10

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