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LOV Proteins Photobiophysics

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Encyclopedia of Biophysics

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Synonyms

FAD = Flavin adenine dinucleotide; FMN = Flavin mononucleotide = riboflavin 5′-phosphate; LOV (light, oxygen, voltage) domains: blue light sensing units of ca. 110 aa; LOV390 = FMN(C4a)-Cys adduct, the product of LOV domain photochemistry; LOV450 = dark-adapted state of a LOV domain; Riboflavin = 7,8-Dimethyl-10-(1-deoxy-d-ribitol-1-yl)isoalloxazine

Introduction

LOV proteins with UVA/blue light (BL) sensitivity are photoreceptors employing LOV (light, oxygen, voltage) domains as photosensory modules linked to a large variety of effector functions in plants, fungi, bacteria, and archaea (Glantz et al. 2016; Losi and Gärtner 2017). LOV domains belong to the PAS (PerArntSim) superfamily (Gu et al. 2000) and present a characteristic α/β fold where the secondary structure elements are named Aβ,Bβ,Cα,Dα,Eα,Fα,Gβ,Hβ, and Iβ, starting from the N-terminus (Zoltowski and Gardner 2011). They bear a fully oxidized riboflavin, flavin mononucleotide (FMN), or flavin adenine dinucleotide...

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Author information

Authors and Affiliations

  1. Department of Mathematical, Physical and Computer Sciences University of Parma, Parma, Italy

    Aba Losi

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  1. Aba Losi
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Correspondence to Aba Losi .

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Editors and Affiliations

  1. University Leicester MRC Centre, Leicester, UK

    Gordon Roberts

  2. Dept Biochemistry, University of Oxford, Oxford, UK

    Anthony Watts

Section Editor information

  1. Department of Physics, Institute of Experimental Physics, Free University of Berlin, Berlin, Germany

    Ulrike Alexiev

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© 2020 European Biophysical Societies' Association (EBSA)

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Losi, A. (2020). LOV Proteins Photobiophysics. In: Roberts, G., Watts, A. (eds) Encyclopedia of Biophysics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35943-9_800-1

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  • DOI: https://doi.org/10.1007/978-3-642-35943-9_800-1

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  • Print ISBN: 978-3-642-35943-9

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