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Succinic acid (HOOCCH2CH2COOH) is a dicarboxylic acid which plays an important role in the citric acid cycle. The name comes from Latin succinum, meaning amber, from which the acid was first isolated. The carboxylate anion is called succinate. Succinic acid has a melting point of 185 °C and a boiling point of 235 °C.
In the citric acid cycle, succinic acid donates electrons to FAD (flavin adenine dinucleotide) and ultimately to the electron transport chain by the reaction
$$ {\mathrm Succinate}+{\mathrm FAD}\to {\mathrm Fumarate}+{{\mathrm FADH}}_2. $$
This reaction is catalyzed by the enzyme succinate dehydrogenase.
Succinic acid has been produced in various prebiotic experiments and has been found in carbonaceous chondrite meteorites.
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Cleaves, H.J. (2022). Succinic Acid. In: Gargaud, M., et al. Encyclopedia of Astrobiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27833-4_1532-4
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DOI: https://doi.org/10.1007/978-3-642-27833-4_1532-4
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Succinic Acid- Published:
- 08 February 2023
DOI: https://doi.org/10.1007/978-3-642-27833-4_1532-4
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Succinic Acid- Published:
- 22 April 2015
DOI: https://doi.org/10.1007/978-3-642-27833-4_1532-3