SpringerLink
Log in

Kidney Transplant and Peritoneal Dialysis

  • Living reference work entry
  • First Online:
Nolph and Gokal's Textbook of Peritoneal Dialysis

  • 20 Accesses

Abstract

Kidney transplantation is associated with improved survival and quality of life for patients with end-stage renal disease (ESRD). Due to the shortage of donor kidneys, the waitlist for kidney transplantation is long, and most patients with ESRD tend to need dialysis as a bridge for kidney transplantation. This chapter will review the characteristics of ESRD patients on peritoneal dialysis (HD) and hemodialysis (HD) and explore whether differences in modalities or patient features contribute to the differences if any, in rates of transplantation and transplant outcomes for these patients.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Institutional subscriptions

Similar content being viewed by others

References

  1. Hart A, et al. OPTN/SRTR 2017 annual data report: kidney. Am J Transplant. 2019;19(Suppl 2):19–123.

    Article  PubMed  Google Scholar 

  2. Saran R, et al. US renal data system 2018 annual data report: epidemiology of kidney disease in the United States. Am J Kidney Dis. 2019;73(3S1):A7–8.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Wolfe RA, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med. 1999;341(23):1725–30.

    Article  CAS  PubMed  Google Scholar 

  4. Tonelli M, et al. Systematic review: kidney transplantation compared with dialysis in clinically relevant outcomes. Am J Transplant. 2011;11(10):2093–109.

    Article  CAS  PubMed  Google Scholar 

  5. Fiebiger W, Mitterbauer C, Oberbauer R. Health-related quality of life outcomes after kidney transplantation. Health Qual Life Outcomes. 2004;2:2.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Fisher R, et al. Quality of life after renal transplantation. J Clin Nurs. 1998;7(6):553–63.

    Article  CAS  PubMed  Google Scholar 

  7. Kostro JZ, et al. Quality of life after kidney transplantation: a prospective study. Transplant Proc. 2016;48(1):50–4.

    Article  CAS  PubMed  Google Scholar 

  8. Ozcan H, et al. Kidney transplantation is superior to hemodialysis and peritoneal dialysis in terms of cognitive function, anxiety, and depression symptoms in chronic kidney disease. Transplant Proc. 2015;47(5):1348–51.

    Article  CAS  PubMed  Google Scholar 

  9. Sayin A, Mutluay R, Sindel S. Quality of life in hemodialysis, peritoneal dialysis, and transplantation patients. Transplant Proc. 2007;39(10):3047–53.

    Article  CAS  PubMed  Google Scholar 

  10. Schweitzer EJ, et al. The shrinking renal replacement therapy "break-even" point. Transplantation. 1998;66(12):1702–8.

    Article  CAS  PubMed  Google Scholar 

  11. Eggers P. Comparison of treatment costs between dialysis and transplantation. Semin Nephrol. 1992;12(3):284–9.

    CAS  PubMed  Google Scholar 

  12. Bunnapradist S, Danovitch GM. Evaluation of adult kidney transplant candidates. Am J Kidney Dis. 2007;50(5):890–8.

    Article  PubMed  Google Scholar 

  13. Rossi A. Evaluation of the potential renal transplant recipient, in UpToDate. Waltham: UpToDate Inc; 2019.

    Google Scholar 

  14. Sibulesky L, et al. Landscape of kidney transplantation in patients with compensated liver disease: results of a survey of transplant surgeons in the United States. Transplant Proc. 2016;48(10):3268–73.

    Article  CAS  PubMed  Google Scholar 

  15. Paramesh AS, et al. Kidney transplantation alone in ESRD patients with hepatitis C cirrhosis. Transplantation. 2012;94(3):250–4.

    Article  CAS  PubMed  Google Scholar 

  16. Eason JD, et al. Proceedings of consensus conference on simultaneous liver kidney transplantation (SLK). Am J Transplant. 2008;8(11):2243–51.

    Article  CAS  PubMed  Google Scholar 

  17. Israni AK, et al. New national allocation policy for deceased donor kidneys in the United States and possible effect on patient outcomes. J Am Soc Nephrol. 2014;25(8):1842–8.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Meier-Kriesche HU, Kaplan B. Waiting time on dialysis as the strongest modifiable risk factor for renal transplant outcomes: a paired donor kidney analysis. Transplantation. 2002;74(10):1377–81.

    Article  PubMed  Google Scholar 

  19. Meier-Kriesche HU, et al. Effect of waiting time on renal transplant outcome. Kidney Int. 2000;58(3):1311–7.

    Article  CAS  PubMed  Google Scholar 

  20. Jay CL, et al. Reassessing preemptive kidney transplantation in the United States: are we making progress? Transplantation. 2016;100(5):1120–7.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Kasiske BL, et al. Preemptive kidney transplantation: the advantage and the advantaged. J Am Soc Nephrol. 2002;13(5):1358–64.

    Article  PubMed  Google Scholar 

  22. Mange KC, Joffe MM, Feldman HI. Effect of the use or nonuse of long-term dialysis on the subsequent survival of renal transplants from living donors. N Engl J Med. 2001;344(10):726–31.

    Article  CAS  PubMed  Google Scholar 

  23. Vats AN, et al. Pretransplant dialysis status and outcome of renal transplantation in North American children: a NAPRTCS study. North American Pediatric Renal Transplant Cooperative study. Transplantation. 2000;69(7):1414–9.

    Article  CAS  PubMed  Google Scholar 

  24. Prezelin-Reydit M, et al. Prolonged dialysis duration is associated with graft failure and mortality after kidney transplantation: results from the French transplant database. Nephrol Dial Transplant. 2019;34(3):538–45.

    Article  CAS  PubMed  Google Scholar 

  25. Snyder JJ, et al. A comparison of transplant outcomes in peritoneal and hemodialysis patients. Kidney Int. 2002;62(4):1423–30.

    Article  PubMed  Google Scholar 

  26. Inrig JK, et al. Mortality by dialysis modality among patients who have end-stage renal disease and are awaiting renal transplantation. Clin J Am Soc Nephrol. 2006;1(4):774–9.

    Article  PubMed  Google Scholar 

  27. Diaz-Buxo JA, Burgess WP. Is weight gain inevitable in most chronic peritoneal dialysis patients? Adv Perit Dial. 1992;8:334–9.

    CAS  PubMed  Google Scholar 

  28. Little J, et al. Longitudinal lipid profiles on CAPD: their relationship to weight gain, comorbidity, and dialysis factors. J Am Soc Nephrol. 1998;9(10):1931–9.

    Article  CAS  PubMed  Google Scholar 

  29. Lievense H, et al. Relationship of body size and initial dialysis modality on subsequent transplantation, mortality and weight gain of ESRD patients. Nephrol Dial Transplant. 2012;27(9):3631–8.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Mehrotra R, et al. The current state of peritoneal dialysis. J Am Soc Nephrol. 2016;27(11):3238–52.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  31. Wilk AR, Beck J, Kucheryavaya MAY. The kidney allocation system (KAS): the first two years. United Network for Organ Sharing; 2017.

    Google Scholar 

  32. van Biesen W, et al. The impact of the pre-transplant renal replacement modality on outcome after cadaveric kidney transplantation: the Ghent experience. Contrib Nephrol. 2006;150:254–8.

    Article  PubMed  Google Scholar 

  33. Van Biesen W, et al. Peritoneal dialysis favorably influences early graft function after renal transplantation compared to hemodialysis. Transplantation. 2000;69(4):508–14.

    Article  PubMed  Google Scholar 

  34. Cacciarelli TV, et al. The influence of mode of dialysis pretransplantation on long-term renal allograft outcome. Ren Fail. 1993;15(4):545–50.

    Article  CAS  PubMed  Google Scholar 

  35. Song SH, et al. Outcomes of kidney recipients according to mode of pretransplantation renal replacement therapy. Transplant Proc. 2016;48(7):2461–3.

    Article  CAS  PubMed  Google Scholar 

  36. Lin HT, et al. Impact of the pretransplant dialysis modality on kidney transplantation outcomes: a nationwide cohort study. BMJ Open. 2018;8(6):e020558.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Perez Fontan M, et al. Delayed graft function after renal transplantation in patients undergoing peritoneal dialysis and hemodialysis. Adv Perit Dial. 1996;12:101–4.

    CAS  PubMed  Google Scholar 

  38. Bleyer AJ, et al. Dialysis modality and delayed graft function after cadaveric renal transplantation. J Am Soc Nephrol. 1999;10(1):154–9.

    Article  CAS  PubMed  Google Scholar 

  39. Debska-Slizien A, et al. Paired analysis of outcomes after kidney transplantation in peritoneal and hemodialysis patients. Transplant Proc. 2018;50(6):1646–53.

    Article  CAS  PubMed  Google Scholar 

  40. Tang M, Li T, Liu H. A comparison of transplant outcomes in peritoneal and hemodialysis patients: a meta-analysis. Blood Purif. 2016;42(2):170–6.

    Article  PubMed  Google Scholar 

  41. Jain D, Haddad DB, Goel N. Choice of dialysis modality prior to kidney transplantation: does it matter? World J Nephrol. 2019;8(1):1–10.

    Article  PubMed  PubMed Central  Google Scholar 

  42. Weinstein T, et al. Cytokine production by mononuclear cells from patients with chronic renal failure. Isr J Med Sci. 1993;29(4):183–6.

    CAS  PubMed  Google Scholar 

  43. Hakim RM, Wingard RL, Parker RA. Effect of the dialysis membrane in the treatment of patients with acute renal failure. N Engl J Med. 1994;331(20):1338–42.

    Article  CAS  PubMed  Google Scholar 

  44. Van Loo AA, et al. Pretransplantation hemodialysis strategy influences early renal graft function. J Am Soc Nephrol. 1998;9(3):473–81.

    Article  PubMed  Google Scholar 

  45. Molnar MZ, et al. Dialysis modality and outcomes in kidney transplant recipients. Clin J Am Soc Nephrol. 2012;7(2):332–41.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  46. Caliskan Y, et al. Effect of pre-transplant dialysis modality on kidney transplantation outcome. Perit Dial Int. 2009;29(Suppl 2):S117–22.

    Article  PubMed  Google Scholar 

  47. Yang Q, et al. Influence of dialysis modality on renal transplant complications and outcomes. Clin Nephrol. 2009;72(1):62–8.

    Article  CAS  PubMed  Google Scholar 

  48. Ardalan M, et al. Effect of dialysis modality on transplantation outcome in living-donor renal transplantation. Nephro-Urology Monthly 2011;3(4):285–90.

    Google Scholar 

  49. Keller AK, Jorgensen TM, Jespersen B. Identification of risk factors for vascular thrombosis may reduce early renal graft loss: a review of recent literature. J Transp Secur. 2012;2012:793461.

    Google Scholar 

  50. McDonald RA, et al. Pretransplant peritoneal dialysis and graft thrombosis following pediatric kidney transplantation: a NAPRTCS report. Pediatr Transplant. 2003;7(3):204–8.

    Article  PubMed  Google Scholar 

  51. Ojo AO, et al. Dialysis modality and the risk of allograft thrombosis in adult renal transplant recipients. Kidney Int. 1999;55(5):1952–60.

    Article  CAS  PubMed  Google Scholar 

  52. Vaziri ND, et al. Coagulation cascade, fibrinolytic system, antithrombin III, protein C and protein S in patients maintained on continuous ambulatory peritoneal dialysis. Thromb Res. 1989;53(2):173–80.

    Article  CAS  PubMed  Google Scholar 

  53. van der Vliet JA, et al. Increased incidence of renal allograft thrombosis after continuous ambulatory peritoneal dialysis. Clin Transpl. 1996;10(1 Pt 1):51–4.

    Google Scholar 

  54. Perez Fontan M, et al. Peritoneal dialysis is not a risk factor for primary vascular graft thrombosis after renal transplantation. Perit Dial Int. 1998;18(3):311–6.

    CAS  PubMed  Google Scholar 

  55. Goldfarb-Rumyantzev AS, et al. The role of pretransplantation renal replacement therapy modality in kidney allograft and recipient survival. Am J Kidney Dis. 2005;46(3):537–49.

    Article  PubMed  Google Scholar 

  56. Dipalma T, et al. Pre-transplant dialysis modality does not influence short- or long-term outcome in kidney transplant recipients: analysis of paired kidneys from the same deceased donor. Clin Transpl. 2016;30(9):1097–107.

    Article  Google Scholar 

  57. Schwenger V, et al. The role of pretransplant dialysis modality on renal allograft outcome. Nephrol Dial Transplant. 2011;26(11):3761–6.

    Article  PubMed  Google Scholar 

  58. Resende L, et al. Influence of dialysis duration and modality on kidney transplant outcomes. Transplant Proc. 2009;41(3):837–9.

    Article  CAS  PubMed  Google Scholar 

  59. Cosio FG, et al. Patient survival after renal transplantation: I. the impact of dialysis pre-transplant. Kidney Int. 1998;53(3):767–72.

    Article  CAS  PubMed  Google Scholar 

  60. Tobin G. New-onset diabetes after transplant (NODAT) in kidney transplant recipients, in UpToDate. Waltham: UpToDate Inc; 2019.

    Google Scholar 

  61. Madziarska K, et al. The increased risk of post-transplant diabetes mellitus in peritoneal dialysis-treated kidney allograft recipients. Nephrol Dial Transplant. 2011;26(4):1396–401.

    Article  PubMed  Google Scholar 

  62. Seifi S, et al. Posttransplant diabetes mellitus: incidence and risk factors. Transplant Proc. 2009;41(7):2811–3.

    Article  CAS  PubMed  Google Scholar 

  63. Courivaud C, et al. Impact of pre-transplant dialysis modality on post-transplant diabetes mellitus after kidney transplantation. Clin Transpl. 2011;25(5):794–9.

    Article  Google Scholar 

  64. Issa N, Kukla A. Peritoneal dialysis immediately after kidney transplantation. Adv Perit Dial. 2014;30:83–6.

    PubMed  Google Scholar 

  65. Dombros N, et al. European best practice guidelines for peritoneal dialysis. 9 PD and transplantation. Nephrol Dial Transplant. 2005;20(Suppl 9):ix34–5.

    PubMed  Google Scholar 

  66. Palmer JA, et al. Peritoneal dialysis catheter infections in children after renal transplantation: choosing the time of removal. Pediatr Nephrol. 1994;8(6):715–8.

    Article  CAS  PubMed  Google Scholar 

  67. Arbeiter K, et al. Timing of peritoneal dialysis catheter removal after pediatric renal transplantation. Perit Dial Int. 2001;21(5):467–70.

    Article  CAS  PubMed  Google Scholar 

  68. Melek E, et al. Timing for removal of peritoneal dialysis catheters in pediatric renal transplant patients. Exp Clin Transplant. 2016;14(Suppl 3):74–7.

    PubMed  Google Scholar 

  69. Warren J, et al. Should peritoneal dialysis catheters be removed at the time of kidney transplantation? Can Urol Assoc J. 2012;6(5):376–8.

    Article  PubMed  PubMed Central  Google Scholar 

  70. Gokal R, Kost S. Peritoneal dialysis immediately post transplantation. Adv Perit Dial. 1999;15:112–5.

    CAS  PubMed  Google Scholar 

  71. Yan T, et al. Hemodialysis or peritoneal dialysis, which is better for patients with delayed graft function? Kidney Blood Press Res. 2018;43(6):1813–21.

    Article  PubMed  Google Scholar 

  72. Peluso G, et al. Our timing to remove peritoneal catheter dialysis after kidney transplant. Transplant Proc. 2019;51(1):160–3.

    Article  CAS  PubMed  Google Scholar 

  73. Jones RE, et al. Peritoneal dialysis is feasible as a bridge to combined liver-kidney transplant. Perit Dial Int. 2018;38(1):63–5.

    Article  PubMed  Google Scholar 

  74. Chou CY, et al. Peritoneal dialysis is associated with a better survival in cirrhotic patients with chronic kidney disease. Medicine (Baltimore). 2016;95(4):e2465.

    Article  PubMed  Google Scholar 

  75. Helal I, et al. Impact of dialysis modality on kidney transplantation outcomes. J Biomed Sci Eng. 2015;08(02):6.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Nephrology, Department of Medicine, University of Texas Southwestern, Dallas, TX, USA

    Lee Anderson

  2. Associate Professor of Medicine, Division of Nephrology, University of Missouri-Columbia, Columbia, MO, USA

    Preethi Yerram

  3. Staff Physician-Nephrology Section, Harry S Truman Veterans Administration Hospital, Columbia, MO, USA

    Preethi Yerram

  4. Associate Professor of Medicine (Clinical Scholar Track), Division of Nephrology, Medical Director of Kidney Transplant Program - Banner University Medical Center – Tucson, AZ, USA

    Venkatesh Kumar Ariyamuthu

Authors
  1. Lee Anderson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Preethi Yerram
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Venkatesh Kumar Ariyamuthu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Lee Anderson .

Editor information

Editors and Affiliations

  1. Nephrology, School of Medicine Department of Medicine Division of, Columbia, MO, USA

    Ramesh Khanna

  2. Dept. Medicine Div. Nephrology, University of Amsterdam Academic Medical Center, Amsterdam, The Netherlands

    Raymond T. Krediet

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Anderson, L., Yerram, P., Ariyamuthu, V.K. (2022). Kidney Transplant and Peritoneal Dialysis. In: Khanna, R., Krediet, R.T. (eds) Nolph and Gokal's Textbook of Peritoneal Dialysis. Springer, Cham. https://doi.org/10.1007/978-3-319-90760-4_40-1

Download citation

  • DOI: https://doi.org/10.1007/978-3-319-90760-4_40-1

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-90760-4

  • Online ISBN: 978-3-319-90760-4

  • eBook Packages: Springer Reference MedicineReference Module Medicine

Publish with us

Policies and ethics

Search

Navigation