Conditioned Place Preference

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Encyclopedia of Animal Cognition and Behavior

General Introduction

The conditioned place preference (CPP) procedure has been widely used in pharmacology, learning, and behavioral neuroscience. Its most common, but not exclusive, application has been in studying the rewarding and/or aversive properties of drugs and as a screening tool for drug abuse potential (e.g., Bardo and Bevins 2000; Tzschentke 1998). Although there are many methodological differences, the general CPP procedure consists of presenting a rewarding or aversive stimulus in the presence of one distinct chamber on one day and a neutral stimulus (e.g., vehicle) in another distinct chamber on alternating days. After several conditioning days, subjects receive a choice test that involves access to the entire apparatus without the presence of the stimuli. A CPP is established if subjects spend significantly more time in the compartment paired with the rewarding or aversive stimulus. If subjects spend less time in a compartment paired with a stimulus, they may be...

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Correspondence to Chana K. Akins .

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Akins, C.K., Eaton, S.E., Bolin, B.L. (2022). Conditioned Place Preference. In: Vonk, J., Shackelford, T.K. (eds) Encyclopedia of Animal Cognition and Behavior. Springer, Cham. https://doi.org/10.1007/978-3-319-55065-7_1303

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