Abstract
Clinical practice guidelines (CPGs) play an important role in medical practice, and computerized support to CPGs is now one of the most central areas of research in Artificial Intelligence in medicine. In recent years, many groups have developed different computer-assisted management systems of Computer Interpretable Guidelines (CIGs). From one side, there are several commonalities between different approaches; from the other side, each approach has its own peculiarities and is geared towards the treatment of specific phenomena. In our work, we propose a form of generalization: instead of defining “yet another CIG system”, we propose a META-GLARE, a “meta”-system (or, in other words, a shell) to define new CIG systems. From one side, we try to capture the commonalities, by providing (i) a general tool for the acquisition, consultation and execution of hierarchical directed graphs (representing the control flow of actions in CIGs), parameterized over the types of nodes and of arcs constituting it, and (ii) a library of different elementary components of guidelines nodes (actions) and arcs, in which each type definition involves the specification of how objects of this type can be acquired, consulted and executed. From the other side, we provide generality and flexibility, by allowing free aggregations of such elementary components to define new primitive node and arc types. In this paper, we first propose META-GLARE general architecture and then, for the sake of brevity, we will focus only on the acquisition issue.
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Notes
- 1.
The guideline for ischemic ictus has been developed by Azienda Ospedaliera S. Giovanni Battista in Turin, one of the largest hospitals in Italy.
- 2.
The treatment of versioning is outside the goals of our present work. However, we are planning to face this issue in the future, also taking advantage of the formal approach we already devised [24].
References
Gordon, C., Christensen, J.P. (eds.): Health Telematics for Clinical Guidelines and Protocols. IOS Press, Amsterdam (1995)
Fridsma, D.B. (Guest ed.): Special issue on workflow management and clinical guidelines. J. Am. Med. Inform. Assoc. 22(1), 1–80 (2001)
ten Teije A., Miksch, S., Lucas, P. (eds.): Computer-Based Medical Guidelines and Protocols: A Primer and Current Trends. IOS Press, Amsterdam (2008)
Peleg, M., Tu, S., Bury, J., Ciccarese, P., Fox, J., Greenes, R.A., Hall, R., Johnson, P.D., Jones, N., Kumar, A., Miksch, S., Quaglini, S., Seyfang, A., Shortliffe, E.H., Stefanelli, M.: Comparing computer-interpretable guideline models: a case-study approach. J. Am. Med. Inform. Assoc. 10(1), 52–68 (2003)
Miksch, S., Shahar Y., Johnson, P.: Asbru: a task-specific, intention-based, and time-oriented language for representing skeletal plans. In: Proceedings of 7th Workshop on Knowledge Engineering Methods and Languages, pp. 9–20 (1997)
Musen, M.A., Tu, S.W., Das, A.K., Shahar, Y.: EON: a component-based approach to automation of protocol-directed therapy. J. Am. Med. Inform. Assoc. 3(6), 367–388 (1996)
Ohno-Machado, L., Gennari, J.H., Murphy, S., Jain, N.L., Tu, S.W., Oliver, D.E., et al.: The guideline interchange format: a model for representing guidelines. JAMIA 5(4), 357–372 (1998)
Peleg, M., Boxawala, A.A., et al.: GLIF3: the evolution of a guideline representation format. In: Proceedings of AMIA’00, pp. 645–649 (2000)
Quaglini, S., Stefanelli, M., Cavallini, A., Miceli, G., Fassino, C., Mossa, C.: Guideline-based careflow systems. Artif. Intell. Med. 20(1), 5–22 (2000)
Johnson, P.D., Tu, S.W., Booth, N., Sugden, B., Purves, I.N.: Using scenarios in chronic disease management guidelines for primary care. In: Proceedings of the AMIA Annual Fall Symposium 2000, pp. 389–393 (2000)
Fox, J., Johns, N., Rahmanzadeh, A., Thomson, R.: Disseminating medical knowledge: the PROforma approach. Artif. Intell. Med. 14, 157–181 (1998)
Peleg, M.: Computer-interpretable clinical guidelines: a methodological review. J. Biomed. Inform. 46(4), 744–763 (2013)
Terenziani, P., Molino, G., Torchio, M.: A modular approach for representing and executing clinical guidelines. Artif. Intell. Med. 23(3), 249–276 (2001)
Anselma, L., Bottrighi, A., Molino, G., Montani, S., Terenziani, P., Torchio, M.: Supporting knowledge-based decision making in the medical context: the GLARE approach. IJKBO 1(1), 42–60 (2011)
Anselma, L., Terenziani, P., Montani, S., Bottrighi, A.: Towards a comprehensive treatment of repetitions, periodicity and temporal constraints in clinical guidelines. Artif. Intell. Med. 38(2), 171–195 (2006)
Leonardi, G., Bottrighi, A., Galliani, G., Terenziani, P., Messina, A., Della Corte, F.: Exceptions handling within GLARE clinical guideline framework. In: Proceedings of AMIA Annual Symposium 2012, pp. 512–521 (2012)
Johnson, S.C.: Yacc: Yet Another Compiler-Compiler, vol. 32. Bell Laboratories, Murray Hill (1975)
Hripcsak, G.: Writing Arden syntax medical logic modules. Comput. Biol. Med. 24(5), 331–363 (1994)
http://docs.oracle.com/javase/tutorial/deployment/applet/index.html. Accessed 30 March 2014
http://www.postgresql.org. Accessed 30 March 2014
http://www.w3.org/standards/xml/schema. Accessed 4 April 2014
Naur, P. (ed.): Revised report on the algorithmic language ALGOL 60. Commun. ACM 3(5), 299–314 (1960)
http://www.jgraph.com/. Accessed 2 April 2014
Anselma, L., Bottrighi, A., Montani, S., Terenziani, P.: Managing proposals and evaluations of updates to medical knowledge: theory and applications. J. Biomed. Inform. 46(2), 363–376 (2013)
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The research described in this paper has been partially supported by Compagnia San Paolo, within the GINSENG project.
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Terenziani, P., Bottrighi, A., Lovotti, I., Rubrichi, S. (2014). META-GLARE: A Meta-System for Defining Your Own CIG System: Architecture and Acquisition. In: Miksch, S., Riaño, D., ten Teije, A. (eds) Knowledge Representation for Health Care. KR4HC 2014. Lecture Notes in Computer Science(), vol 8903. Springer, Cham. https://doi.org/10.1007/978-3-319-13281-5_7
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