Abstract
In the pathophysiological mechanism of cerebral vasospasm following subarachnoid haemorhage (SAH), many biochemical processes are involved. To understand these complicated biochemical processes, it is better to summarize them into two processes: the extracellular process involving vascular smooth muscle cells, and the intracellular process. Most studies for the extracellular process are searching for spasmogenic substances. In studies of the intracellular mechanism, the roles of intracellular calcium, myosin light chain phosphorylation, intracellular signal transduction mechanisms, and actin are included. It is extremely important to understand how these integrate, interact, and inhibit each other to clarify the pathophysiological mechanism of post SAH cerebral vasospasm.
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© 2008 Springer-Verlag
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Nishizawa, S. (2008). Vasospasm biochemistry. In: Kırış, T., Zhang, J.H. (eds) Cerebral Vasospasm. Acta Neurochirurgica Supplement, vol 104. Springer, Vienna. https://doi.org/10.1007/978-3-211-75718-5_10
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DOI: https://doi.org/10.1007/978-3-211-75718-5_10
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