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Spondyloarthritis

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Compendium of Inflammatory Diseases

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Synonyms

Ankylosing spondylitis; Arthritis associated with inflammatory bowel disease; Juvenile spondyloarthritis; Psoriatic arthritis; Spondyloarthropathies; Undifferentiated spondyloarthritis

Definition

Spondyloarthritis (SpA) is a term that covers a group of interrelated heterogeneous diseases that share the characteristic of axial engagement, asymmetric oligoarthritis, and enthesitis and are seronegative for rheumatoid factor (Gran and Skomsvoll 1997; van der Linden and van der Heijde 1998). The most relevant immunogenetic feature is the remarkable familiar aggregation and the association with the histocompatibility antigen, HLA-B27 (González-Roces and Alvarez 1996).

The concept of SpA has been gradually developed throughout the last 30 years. At present, it includes different conditions such as ankylosing spondylitis (AS), reactive arthritis (ReA), psoriatic arthritis (PsA), arthritis associated with inflammatory bowel diseases (IBD), and the juvenile forms of each of these...

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Authors and Affiliations

  1. Section of Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina

    Fernando A. Sommefleck, Emilce E. Schneeberger & Gustavo Citera

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  1. Fernando A. Sommefleck
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  2. Emilce E. Schneeberger
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  1. Inst of Clinical Pharmacology Haus 74/75, JW Goethe University Frankfurt Fraunhofer IME, Frankfurt, Germany

    Michael J. Parnham

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Sommefleck, F.A., Schneeberger, E.E., Citera, G. (2016). Spondyloarthritis. In: Parnham, M. (eds) Compendium of Inflammatory Diseases. Birkhäuser, Basel. https://doi.org/10.1007/978-3-0348-0620-6_191-1

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