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Biomarkers of Diabetic Foot Ulcers and Its Healing Progress

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The Diabetic Foot

Part of the book series: Contemporary Diabetes ((CDI))

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Abstract

There are urgent, unmet needs in the field of biomarkers of diabetic wound healing. Rapidly develo** molecular technologies supported by the parallel, robust progress in biostatistical and machine learning approaches are offering more granular insights into the disease processes and unraveling potential biomarkers. These methodological and computational innovations are tremendously accelerating biomarker research. National Institute of Diabetes and Digestive and Kidney Diseases has recently funded the Diabetic Foot Consortium, the largest initiative to date aiming to develop and validate biomarkers of diabetic foot ulcers; whereas the Food and Drug Administration and the National Institutes of Health offer an important glossary of nomenclature to help researchers navigate through different types of biomarkers. Multi-molecule signatures rather than single biomarker measurements will likely guide the diabetic wound healing course in the near future.

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Authors and Affiliations

  1. Section on Genetics and Epidemiology, Joslin Diabetes Center, Boston, MA, USA

    Monika A. Niewczas & Hetal Shah

  2. Department of Medicine, Harvard Medical School, Boston, MA, USA

    Monika A. Niewczas & Hetal Shah

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  1. Monika A. Niewczas
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  2. Hetal Shah
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Correspondence to Monika A. Niewczas .

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Editors and Affiliations

  1. The Rongxiang Xu, MD, Center for Regenerative Therapeutics, Boston, MA, USA

    Aristidis Veves

  2. Division of Podiatric Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA

    John M. Giurini

  3. Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA

    Marc L. Schermerhorn

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Niewczas, M.A., Shah, H. (2024). Biomarkers of Diabetic Foot Ulcers and Its Healing Progress. In: Veves, A., Giurini, J.M., Schermerhorn, M.L. (eds) The Diabetic Foot. Contemporary Diabetes. Humana, Cham. https://doi.org/10.1007/978-3-031-55715-6_18

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