Abstract
Synaptic plasticity is a critical underlying mechanism of learning and memory. There is extensive evidence that neural activity at one point in time can affect the properties of subsequent synaptic plasticity (for example, whether a synapse becomes potentiated or depressed, and for how long). That is, synaptic plasticity itself can be dynamically regulated by the prior history of activity. Such “metaplasticity” can be expressed homosynaptically, heterosynaptically, or even heterodendritically. We have studied a form of heterodendritic metaplasticity in the hippocampus that regulates future plasticity via an intercellular signaling cascade, including astrocytes, that culminates in long-term potentiation (LTP) inhibition and long-term depression (LTD) facilitation. Conversely, the synaptic tag and capture hypothesis is a form of intracellular metaplasticity in which the duration of synaptic plasticity is centrally regulated by protein synthesis such that prior neural activity facilitates the longevity of LTP and LTD, either heterosynaptically or heterodendritically. Although on the surface, both mechanisms appear similar in their ability to confer cell-wide regulation of synaptic plasticity, these mechanisms appear somewhat at odds with one another. In this review, we discuss the underlying mechanisms of these two distinct regulatory mechanisms and their potential roles in learning and memory.
Authors Owen D. Jones and Shruthi Sateesh are the joint first authors for this chapter.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Abraham WC (2008, May) Metaplasticity: tuning synapses and networks for plasticity. Nat Rev Neurosci 9(5):387. https://doi.org/10.1038/nrn2356
Abraham WC, Bear MF (1996, Apr) Metaplasticity: the plasticity of synaptic plasticity. Trends Neurosci 19(4):126–130. https://doi.org/10.1016/s0166-2236(96)80018-x
Abraham WC, Huggett A (1997) Induction and reversal of long-term potentiation by repeated high-frequency stimulation in rat hippocampal slices. Hippocampus 7(2):137–145. https://doi.org/10.1002/(SICI)1098-1063(1997)
Abraham WC, Mason-Parker SE, Bear MF, Webb S, Tate WP (2001, Sep 11) Heterosynaptic metaplasticity in the hippocampus in vivo: a BCM-like modifiable threshold for LTP. Proc Natl Acad Sci USA 98(19):10924–10929. https://doi.org/10.1073/pnas.181342098
Abraham WC, Jones OD, Glanzman DL (2019) Is plasticity of synapses the mechanism of long-term memory storage? NPJ Sci Learn 4:9. https://doi.org/10.1038/s41539-019-0048-y
Abudara V, Roux L, Dallerac G, Matias I, Dulong J, Mothet JP, Rouach N, Giaume C (2015, May) Activated microglia impairs neuroglial interaction by opening Cx43 hemichannels in hippocampal astrocytes. Glia 63(5):795–811. https://doi.org/10.1002/glia.22785
Alarcon JM, Barco A, Kandel ER (2006, Jan 4) Capture of the late phase of long-term potentiation within and across the apical and basilar dendritic compartments of CA1 pyramidal neurons: synaptic tagging is compartment restricted. J Neurosci 26(1):256–264. https://doi.org/10.1523/JNEUROSCI.3196-05.2006
Araque A, Parpura V, Sanzgiri RP, Haydon PG (1999, May) Tripartite synapses: glia, the unacknowledged partner. Trends Neurosci 22(5):208–215. https://doi.org/10.1016/s0166-2236(98)01349-6
Balducci C, Tonini R, Zianni E, Nazzaro C, Fiordaliso F, Salio M, Vismara L, Gardoni F, Di Luca M, Carli M, Forloni G (2010) Cognitive deficits associated with alteration of synaptic metaplasticity precede plaque deposition in AbetaPP23 transgenic mice. J Alzheimers Dis 21(4):1367–1381. https://doi.org/10.3233/jad-2010-100675
Barbin G, Roisin MP, Zalc B (2001) Tumor necrosis factor alpha activates the phosphorylation of ERK, SAPK/JNK, and P38 kinase in primary cultures of neurons. Neurochem Res 26(2):107–112. https://doi.org/10.1023/a:1011086426652
Bellinger FP, Madamba S, Siggins GR (1993) Interleukin 1 beta inhibits synaptic strength and long-term potentiation in the rat CA1 hippocampus. Brain Res 628(1–2):227–234. https://doi.org/10.1016/0006-8993(93)90959-q
Bernardinelli Y, Salmon C, Jones EV, Farmer WT, Stellwagen D, Murai KK (2011) Astrocytes display complex and localized calcium responses to single-neuron stimulation in the hippocampus. J Neurosci 31(24):8905–8919. https://doi.org/10.1523/JNEUROSCI.6341-10.2011
Bienenstock EL, Cooper LN, Munro PW (1982) Theory for the development of neuron selectivity: orientation specificity and binocular interaction in visual cortex. J Neurosci 2(1):32–48. https://doi.org/10.1523/JNEUROSCI.02-01-00032.1982
Bukalo O, Campanac E, Hoffman DA, Fields RD (2013) Synaptic plasticity by antidromic firing during hippocampal network oscillations. Proc Natl Acad Sci USA 110(13):5175–5180. https://doi.org/10.1073/pnas.1210735110
Bushong EA, Martone ME, Jones YZ, Ellisman MH (2002) Protoplasmic astrocytes in CA1 stratum radiatum occupy separate anatomical domains. J Neurosci 22(1):183–192. https://doi.org/10.1523/JNEUROSCI.22-01-00183.2002
Butler MP, O’Connor JJ, Moynagh PN (2004) Dissection of tumor-necrosis factor-alpha inhibition of long-term potentiation (LTP) reveals a p38 mitogen-activated protein kinase-dependent mechanism which maps to early-but not late-phase LTP. Neuroscience 124(2):319–326. https://doi.org/10.1016/j.neuroscience.2003.11.040
Chang R, Yee KL, Sumbria RK (2017) Tumor necrosis factor alpha inhibition for Alzheimer’s disease. J Cent Nerv Syst Dis 9:1179573517709278. https://doi.org/10.1177/1179573517709278
Chapman PF, White GL, Jones MW, Cooper-Blacketer D, Marshall VJ, Irizarry M, Younkin L, Good MA, Bliss TV, Hyman BT, Younkin SG, Hsiao KK (1999) Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat Neurosci 2(3):271–276. https://doi.org/10.1038/6374
Christie BR, Stellwagen D, Abraham WC (1995) Reduction of the threshold for long-term potentiation by prior theta-frequency synaptic activity. Hippocampus 5(1):52–59. https://doi.org/10.1002/hipo.450050107
Clark IA, Vissel B (2021) Broader insights into understanding tumor necrosis factor and neurodegenerative disease pathogenesis infer new therapeutic approaches. J Alzheimers Dis 79(3):931–948. https://doi.org/10.3233/JAD-201186
Cohen AS, Abraham WC (1996) Facilitation of long-term potentiation by prior activation of metabotropic glutamate receptors. J Neurophysiol 76(2):953–962. https://doi.org/10.1152/jn.1996.76.2.953
Cohen AS, Raymond CR, Abraham WC (1998) Priming of long-term potentiation induced by activation of metabotropic glutamate receptors coupled to phospholipase C. Hippocampus 8(2):160–170. https://doi.org/10.1002/(SICI)1098-1063(1998)8
Cohen AS, Coussens CM, Raymond CR, Abraham WC (1999) Long-lasting increase in cellular excitability associated with the priming of LTP induction in rat hippocampus. J Neurophysiol 82(6):3139–3148. https://doi.org/10.1152/jn.1999.82.6.3139
Cunningham AJ, Murray CA, O’Neill LA, Lynch MA, O’Connor JJ (1996) Interleukin-1 beta (IL-1 beta) and tumour necrosis factor (TNF) inhibit long-term potentiation in the rat dentate gyrus in vitro. Neurosci Lett 203(1):17–20. https://doi.org/10.1016/0304-3940(95)12252-4
Domercq M, Brambilla L, Pilati E, Marchaland J, Volterra A, Bezzi P (2006) P2Y1 receptor-evoked glutamate exocytosis from astrocytes: control by tumor necrosis factor-alpha and prostaglandins. J Biol Chem 281(41):30684–30696. https://doi.org/10.1074/jbc.M606429200
Dudek SM, Fields RD (2002) Somatic action potentials are sufficient for late-phase LTP-related cell signaling. Proc Natl Acad Sci USA 99(6):3962–3967. https://doi.org/10.1073/pnas.062510599
Eschenko O, Ramadan W, Molle M, Born J, Sara SJ (2008) Sustained increase in hippocampal sharp-wave ripple activity during slow-wave sleep after learning. Learn Mem 15(4):222–228. https://doi.org/10.1101/lm.726008
Fakhoury M (2018) Microglia and astrocytes in Alzheimer’s disease: implications for therapy. Curr Neuropharmacol 16(5):508–518. https://doi.org/10.2174/1570159X15666170720095240
Fellin T, Pascual O, Gobbo S, Pozzan T, Haydon PG, Carmignoto G (2004) Neuronal synchrony mediated by astrocytic glutamate through activation of extrasynaptic NMDA receptors. Neuron 43(5):729–743. https://doi.org/10.1016/j.neuron.2004.08.011
Frey U, Morris RG (1997) Synaptic tagging and long-term potentiation. Nature 385(6616):533–536. https://doi.org/10.1038/385533a0
Frey U, Morris RG (1998) Synaptic tagging: implications for late maintenance of hippocampal long-term potentiation. Trends Neurosci 21(5):181–188. https://doi.org/10.1016/s0166-2236(97)01189-2
Gisabella B, Rowan MJ, Anwyl R (2003) Mechanisms underlying the inhibition of long-term potentiation by preconditioning stimulation in the hippocampus in vitro. Neuroscience 121(2):297–305. https://doi.org/10.1016/s0306-4522(03)00440-8
Govindarajan A, Israely I, Huang SY, Tonegawa S (2011) The dendritic branch is the preferred integrative unit for protein synthesis-dependent LTP. Neuron 69(1):132–146. https://doi.org/10.1016/j.neuron.2010.12.008
Habbas S, Santello M, Becker D, Stubbe H, Zappia G, Liaudet N, Klaus FR, Kollias G, Fontana A, Pryce CR, Suter T, Volterra A (2015) Neuroinflammatory TNFalpha impairs memory via astrocyte signaling. Cell 163(7):1730–1741. https://doi.org/10.1016/j.cell.2015.11.023
Hajos N, Ellender TJ, Zemankovics R, Mann EO, Exley R, Cragg SJ, Freund TF, Paulsen O (2009) Maintaining network activity in submerged hippocampal slices: importance of oxygen supply. Eur J Neurosci 29(2):319–327. https://doi.org/10.1111/j.1460-9568.2008.06577.x
Hegemann RU, Abraham WC (2021) Postsynaptic cell firing triggers bidirectional metaplasticity depending on the LTP induction protocol. J Neurophysiol 125(5):1624–1635. https://doi.org/10.1152/jn.00514.2020
Hide I, Tanaka M, Inoue A, Nakajima K, Kohsaka S, Inoue K, Nakata Y (2000) Extracellular ATP triggers tumor necrosis factor-alpha release from rat microglia. J Neurochem 75(3):965–972. https://doi.org/10.1046/j.1471-4159.2000.0750965.x
Holland LL, Wagner JJ (1998) Primed facilitation of homosynaptic long-term depression and depotentiation in rat hippocampus. J Neurosci 18(3):887–894. https://doi.org/10.1523/JNEUROSCI.18-03-00887.1998
Huang YY, Colino A, Selig DK, Malenka RC (1992) The influence of prior synaptic activity on the induction of long-term potentiation. Science 255(5045):730–733. https://doi.org/10.1126/science.1346729
Hulme SR, Jones OD, Ireland DR, Abraham WC (2012) Calcium-dependent but action potential-independent BCM-like metaplasticity in the hippocampus. J Neurosci 32(20):6785–6794. https://doi.org/10.1523/JNEUROSCI.0634-12.2012
Hulme SR, Jones OD, Raymond CR, Sah P, Abraham WC (2014) Mechanisms of heterosynaptic metaplasticity. Philos Trans R Soc Lond Ser B Biol Sci 369(1633):20130148. https://doi.org/10.1098/rstb.2013.0148
Jones OD, Hulme SR, Abraham WC (2013) Purinergic receptor- and gap junction-mediated intercellular signalling as a mechanism of heterosynaptic metaplasticity. Neurobiol Learn Mem 105:31–39. https://doi.org/10.1016/j.nlm.2013.05.010
Kailainathan S, Piers TM, Yi JH, Choi S, Fahey MS, Borger E, Gunn-Moore FJ, O’Neill L, Lever M, Whitcomb DJ, Cho K, Allen SJ (2016) Activation of a synapse weakening pathway by human Val66 but not Met66 pro-brain-derived neurotrophic factor (proBDNF). Pharmacol Res 104:97–107. https://doi.org/10.1016/j.phrs.2015.12.008
Kawamura M Jr, Kawamura M (2011) Long-term facilitation of spontaneous calcium oscillations in astrocytes with endogenous adenosine in hippocampal slice cultures. Cell Calcium 49(4):249–258. https://doi.org/10.1016/j.ceca.2011.02.009
Kirkwood A, Rioult MG, Bear MF (1996) Experience-dependent modification of synaptic plasticity in visual cortex. Nature 381(6582):526–528. https://doi.org/10.1038/381526a0
Konietzko U, Muller CM (1994) Astrocytic dye coupling in rat hippocampus: topography, developmental onset, and modulation by protein kinase C. Hippocampus 4(3):297–306. https://doi.org/10.1002/hipo.450040313
Le Ray D, Fernandez De Sevilla D, Belen Porto A, Fuenzalida M, Buno W (2004) Heterosynaptic metaplastic regulation of synaptic efficacy in CA1 pyramidal neurons of rat hippocampus. Hippocampus 14(8):1011–1025. https://doi.org/10.1002/hipo.20021
Li Q, Rothkegel M, **ao ZC, Abraham WC, Korte M, Sajikumar S (2014) Making synapses strong: metaplasticity prolongs associativity of long-term memory by switching synaptic tag mechanisms. Cereb Cortex 24(2):353–363. https://doi.org/10.1093/cercor/bhs315
Li Q, Korte M, Sajikumar S (2016) Ubiquitin-proteasome system inhibition promotes long-term depression and synaptic tagging/capture. Cereb Cortex 26(6):2541–2548. https://doi.org/10.1093/cercor/bhv084
Li Q, Navakkode S, Rothkegel M, Soong TW, Sajikumar S, Korte M (2017) Metaplasticity mechanisms restore plasticity and associativity in an animal model of Alzheimer’s disease. Proc Natl Acad Sci USA 114(21):5527–5532. https://doi.org/10.1073/pnas.1613700114
Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Munch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, Buckwalter MS, Rowitch DH, Dawson VL, Dawson TM, Stevens B, Barres BA (2017) Neurotoxic reactive astrocytes are induced by activated microglia. Nature 541(7638):481–487. https://doi.org/10.1038/nature21029
MacPherson KP, Sompol P, Kannarkat GT, Chang J, Sniffen L, Wildner ME, Norris CM, Tansey MG (2017) Peripheral administration of the soluble TNF inhibitor XPro1595 modifies brain immune cell profiles, decreases beta-amyloid plaque load, and rescues impaired long-term potentiation in 5xFAD mice. Neurobiol Dis 102:81–95. https://doi.org/10.1016/j.nbd.2017.02.010
Mango D, Saidi A, Cisale GY, Feligioni M, Corbo M, Nistico R (2019) Targeting synaptic plasticity in experimental models of Alzheimer’s disease. Front Pharmacol 10:778. https://doi.org/10.3389/fphar.2019.00778
Martin KC, Kosik KS (2002) Synaptic tagging — who’s it? Nat Rev Neurosci 3(10):813–820. https://doi.org/10.1038/nrn942
Megill A, Tran T, Eldred K, Lee NJ, Wong PC, Hoe HS, Kirkwood A, Lee HK (2015) Defective age-dependent metaplasticity in a mouse model of Alzheimer’s disease. J Neurosci 35(32):11346–11357. https://doi.org/10.1523/JNEUROSCI.5289-14.2015
Mellentin C, Abraham WC (2001) Priming stimulation of group II metabotropic glutamate receptors inhibits the subsequent induction of rat hippocampal long-term depression in vitro. Neurosci Lett 307(1):13–16. https://doi.org/10.1016/s0304-3940(01)01915-2
Min R, Nevian T (2012) Astrocyte signaling controls spike timing-dependent depression at neocortical synapses. Nat Neurosci 15(5):746–753. https://doi.org/10.1038/nn.3075
Mockett B, Coussens C, Abraham WC (2002) NMDA receptor-mediated metaplasticity during the induction of long-term depression by low-frequency stimulation. Eur J Neurosci 15(11):1819–1826. https://doi.org/10.1046/j.1460-9568.2002.02008.x
Navarrete M, Araque A (2008) Endocannabinoids mediate neuron-astrocyte communication. Neuron 57(6):883–893. https://doi.org/10.1016/j.neuron.2008.01.029
Navarrete M, Perea G, Fernandez de Sevilla D, Gomez-Gonzalo M, Nunez A, Martin ED, Araque A (2012) Astrocytes mediate in vivo cholinergic-induced synaptic plasticity. PLoS Biol 10(2):e1001259. https://doi.org/10.1371/journal.pbio.1001259
Navarrete M, Cuartero MI, Palenzuela R, Draffin JE, Konomi A, Serra I, Colie S, Castano-Castano S, Hasan MT, Nebreda AR, Esteban JA (2019) Astrocytic p38alpha MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory. Nat Commun 10(1):2968. https://doi.org/10.1038/s41467-019-10830-9
Nett WJ, Oloff SH, McCarthy KD (2002) Hippocampal astrocytes in situ exhibit calcium oscillations that occur independent of neuronal activity. J Neurophysiol 87(1):528–537. https://doi.org/10.1152/jn.00268.2001
O’Leary DM, O’Connor JJ (1998) Priming of long-term potentiation by prior activation of group I and II metabotropic glutamate receptors in the rat dentate gyrus in vitro. Brain Res 809(1):91–96. https://doi.org/10.1016/s0006-8993(98)00897-x
O’Neill J, Senior T, Csicsvari J (2006) Place-selective firing of CA1 pyramidal cells during sharp wave/ripple network patterns in exploratory behavior. Neuron 49(1):143–155. https://doi.org/10.1016/j.neuron.2005.10.037
Okamoto K, Bosch M, Hayashi Y (2009) The roles of CaMKII and F-actin in the structural plasticity of dendritic spines: a potential molecular identity of a synaptic tag? Physiology (Bethesda) 24:357–366. https://doi.org/10.1152/physiol.00029.2009
Pang KKL, Sharma M, Krishna KK, Behnisch T, Sajikumar S (2019) Long-term population spike-timing-dependent plasticity promotes synaptic tagging but not cross-tagging in rat hippocampal area CA1. Proc Natl Acad Sci USA 116(12):5737–5746. https://doi.org/10.1073/pnas.1817643116
Park P, Kang H, Sanderson TM, Bortolotto ZA, Georgiou J, Zhuo M, Kaang BK, Collingridge GL (2018) The role of calcium-permeable AMPARs in long-term potentiation at principal neurons in the rodent hippocampus. Front Synaptic Neurosci 10:42. https://doi.org/10.3389/fnsyn.2018.00042
Park P, Kang H, Georgiou J, Zhuo M, Kaang B-K, Collingridge GL (2021) Further evidence that CP-AMPARs are critically involved in synaptic tag and capture at hippocampal CA1 synapses. Molecular Brain 14(1):26. https://doi.org/10.1186/s13041-021-00737-2
Perea G, Araque A (2005) Properties of synaptically evoked astrocyte calcium signal reveal synaptic information processing by astrocytes. J Neurosci 25(9):2192–2203. https://doi.org/10.1523/JNEUROSCI.3965-04.2005
Perea G, Navarrete M, Araque A (2009) Tripartite synapses: astrocytes process and control synaptic information. Trends Neurosci 32(8):421–431. https://doi.org/10.1016/j.tins.2009.05.001
Philpot BD, Sekhar AK, Shouval HZ, Bear MF (2001) Visual experience and deprivation bidirectionally modify the composition and function of NMDA receptors in visual cortex. Neuron 29(1):157–169. https://doi.org/10.1016/s0896-6273(01)00187-8
Pinto-Duarte A, Roberts AJ, Ouyang K, Sejnowski TJ (2019) Impairments in remote memory caused by the lack of type 2 IP(3) receptors. Glia 67(10):1976–1989. https://doi.org/10.1002/glia.23679
Ramachandran B, Frey JU (2009) Interfering with the actin network and its effect on long-term potentiation and synaptic tagging in hippocampal CA1 neurons in slices in vitro. J Neurosci 29(39):12167–12173. https://doi.org/10.1523/JNEUROSCI.2045-09.2009
Raymond CR, Thompson VL, Tate WP, Abraham WC (2000) Metabotropic glutamate receptors trigger homosynaptic protein synthesis to prolong long-term potentiation. J Neurosci 20(3):969–976. https://doi.org/10.1523/JNEUROSCI.20-03-00969.2000
Redondo RL, Morris RG (2011) Making memories last: the synaptic tagging and capture hypothesis. Nat Rev Neurosci 12(1):17–30. https://doi.org/10.1038/nrn2963
Redondo R, Morris RGM (2013) Electrophysiological and behavioral approaches to the analysis of synaptic tagging and capture. In: Nguyen P (ed) Multidisciplinary tools for investigating synaptic plasticity. Humana Press, pp 179–195. https://doi.org/10.1007/978-1-62703-517-0_8
Regan P, Piers T, Yi JH, Kim DH, Huh S, Park SJ, Ryu JH, Whitcomb DJ, Cho K (2015) Tau phosphorylation at serine 396 residue is required for hippocampal LTD. J Neurosci 35(12):4804–4812. https://doi.org/10.1523/JNEUROSCI.2842-14.2015
Rossato JI, Moreno A, Genzel L, Yamasaki M, Takeuchi T, Canals S, Morris RGM (2018) Silent learning. Curr Biol 28(21):3508–3515 e3505. https://doi.org/10.1016/j.cub.2018.09.012
Rush AM, Wu J, Rowan MJ, Anwyl R (2002) Group I metabotropic glutamate receptor (mGluR)-dependent long-term depression mediated via p38 mitogen-activated protein kinase is inhibited by previous high-frequency stimulation and activation of mGluRs and protein kinase C in the rat dentate gyrus in vitro. J Neurosci 22(14):6121–6128. https://doi.org/10.1523/JNEUROSCI.22-14-06121.2002
Sajikumar S, Frey JU (2004) Late-associativity, synaptic tagging, and the role of dopamine during LTP and LTD. Neurobiol Learn Mem 82(1):12–25. https://doi.org/10.1016/j.nlm.2004.03.003
Sajikumar S, Korte M (2011) Metaplasticity governs compartmentalization of synaptic tagging and capture through brain-derived neurotrophic factor (BDNF) and protein kinase Mzeta (PKMzeta). Proc Natl Acad Sci USA 108(6):2551–2556. https://doi.org/10.1073/pnas.1016849108
Sajikumar S, Navakkode S, Sacktor TC, Frey JU (2005) Synaptic tagging and cross-tagging: the role of protein kinase Mzeta in maintaining long-term potentiation but not long-term depression. J Neurosci 25(24):5750–5756. https://doi.org/10.1523/JNEUROSCI.1104-05.2005
Selkoe DJ (2001) Alzheimer’s disease results from the cerebral accumulation and cytotoxicity of amyloid beta-protein. J Alzheimers Dis 3(1):75–80. https://doi.org/10.3233/jad-2001-3111
Sheridan GK, Moeendarbary E, Pickering M, O’Connor JJ, Murphy KJ (2014) Theta-burst stimulation of hippocampal slices induces network-level calcium oscillations and activates analogous gene transcription to spatial learning. PLoS One 9(6):e100546. https://doi.org/10.1371/journal.pone.0100546
Singh A, Abraham WC (2017) Astrocytes and synaptic plasticity in health and disease. Exp Brain Res 235(6):1645–1655. https://doi.org/10.1007/s00221-017-4928-1
Singh A, Jones OD, Mockett BG, Ohline SM, Abraham WC (2019) Tumor necrosis factor-alpha-mediated metaplastic inhibition of LTP is constitutively engaged in an Alzheimer’s disease model. J Neurosci 39(46):9083–9097. https://doi.org/10.1523/JNEUROSCI.1492-19.2019
Singh A, Sateesh S, Jones OD, Abraham WC (2022) Pathway-specific TNF-mediated metaplasticity in hippocampal area CA1. Sci Rep 12(1):1746. https://doi.org/10.1038/s41598-022-05844-1
Stellwagen D, Malenka RC (2006) Synaptic scaling mediated by glial TNF-alpha. Nature 440(7087):1054–1059. https://doi.org/10.1038/nature04671
Tancredi V, D’Arcangelo G, Grassi F, Tarroni P, Palmieri G, Santoni A, Eusebi F (1992) Tumor necrosis factor alters synaptic transmission in rat hippocampal slices. Neurosci Lett 146(2):176–178. https://doi.org/10.1016/0304-3940(92)90071-e
Taylor DL, Jones F, Kubota ES, Pocock JM (2005) Stimulation of microglial metabotropic glutamate receptor mGlu2 triggers tumor necrosis factor alpha-induced neurotoxicity in concert with microglial-derived Fas ligand. J Neurosci 25(11):2952–2964. https://doi.org/10.1523/JNEUROSCI.4456-04.2005
Verkhratsky A, Olabarria M, Noristani HN, Yeh CY, Rodriguez JJ (2010) Astrocytes in Alzheimer’s disease. Neurotherapeutics 7(4):399–412. https://doi.org/10.1016/j.nurt.2010.05.017
Vyas Y, Montgomery JM, Cheyne JE (2020) Hippocampal deficits in amyloid-beta-related rodent models of Alzheimer’s disease. Front Neurosci 14:266. https://doi.org/10.3389/fnins.2020.00266
Wang H, Wagner JJ (1999) Priming-induced shift in synaptic plasticity in the rat hippocampus. J Neurophysiol 82(4):2024–2028. https://doi.org/10.1152/jn.1999.82.4.2024
Wang Q, Wu J, Rowan MJ, Anwyl R (2005) Beta-amyloid inhibition of long-term potentiation is mediated via tumor necrosis factor. Eur J Neurosci 22(11):2827–2832. https://doi.org/10.1111/j.1460-9568.2005.04457.x
Wang SH, Redondo RL, Morris RG (2010) Relevance of synaptic tagging and capture to the persistence of long-term potentiation and everyday spatial memory. Proc Natl Acad Sci USA 107(45):19537–19542. https://doi.org/10.1073/pnas.1008638107
Yasuda R, Sabatini BL, Svoboda K (2003) Plasticity of calcium channels in dendritic spines. Nat Neurosci 6(9):948–955. https://doi.org/10.1038/nn1112
Young JZ, Nguyen PV (2005) Homosynaptic and heterosynaptic inhibition of synaptic tagging and capture of long-term potentiation by previous synaptic activity. J Neurosci 25(31):7221–7231. https://doi.org/10.1523/JNEUROSCI.0909-05.2005
Youssef FF, Addae JI, Stone TW (2006) NMDA-induced preconditioning attenuates synaptic plasticity in the rat hippocampus. Brain Res 1073-1074:183–189. https://doi.org/10.1016/j.brainres.2005.12.008
Zhao J, Li A, Rajsombath M, Dang Y, Selkoe DJ, Li S (2018) Soluble Abeta oligomers impair dipolar Heterodendritic plasticity by activation of mGluR in the hippocampal CA1 region. iScience 6:138–150. https://doi.org/10.1016/j.isci.2018.07.018
Zhou Q, Homma KJ, Poo MM (2004) Shrinkage of dendritic spines associated with long-term depression of hippocampal synapses. Neuron 44(5):749–757. https://doi.org/10.1016/j.neuron.2004.11.011
Acknowledgments
This research was supported by grants from the Neurological Foundation of New Zealand to W.C.A. and O.D.J. and the New Zealand Health Research Council to W.C.A. and S.S.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2024 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Jones, O.D., Sateesh, S., Abraham, W.C. (2024). Metaplasticity and Synaptic Tag and Capture: Differential Dynamics of Plasticity Regulation in the Hippocampus. In: Sajikumar, S., Abel, T. (eds) Synaptic Tagging and Capture. Springer, Cham. https://doi.org/10.1007/978-3-031-54864-2_4
Download citation
DOI: https://doi.org/10.1007/978-3-031-54864-2_4
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-54863-5
Online ISBN: 978-3-031-54864-2
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)