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Rectal and Vaginal Drug Delivery

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Essential Pharmaceutics

Part of the book series: AAPS Introductions in the Pharmaceutical Sciences ((AAPSINSTR,volume 12))

Abstract

This chapter provides an overview of dosage forms relevant to rectal and vaginal drug delivery. Barriers to drug absorption are discussed and frequently used excipients are covered. The manufacturing and special formulation considerations for drug delivery using suppository formulations are also reviewed.

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Further Reading

Suggested readings for the student include the following texts:

  • Lang B, McGinity JW, Williams RO. Hot melt extrusion – basic principles and pharmaceutical applications. Drug Dev Ind Pharm. 2014;40(9):1133–55. (see page 1150; “Implants” section)

    Article  CAS  PubMed  Google Scholar 

  • Shin S, Byun S. Controlled release of ethinylestradiol from ethylene-vinyl acetate membrane. Int J Pharm. 1996;137(21):95–102.

    Article  CAS  Google Scholar 

  • Anderson GD, Saneto RP. Current oral and non-oral routes of antiepileptic drug delivery. Adv Drug Deliv Rev. 2012;64(10):911–8.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. College of Pharmacy, University of Michigan–Ann Arbor, Ann Arbor, MI, USA

    Ashlee D. Brunaugh

  2. University of Valparaíso, Valparaíso, Chile

    Daniel Moraga-Espinoza & Tania Bahamondez-Canas

  3. College of Pharmacy, The University of Texas at Austin, Austin, TX, USA

    Hugh D. C. Smyth & Robert O. Williams

Authors
  1. Ashlee D. Brunaugh
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  2. Daniel Moraga-Espinoza
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  3. Tania Bahamondez-Canas
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  4. Hugh D. C. Smyth
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  5. Robert O. Williams
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© 2024 The Author(s), under exclusive license to Springer Nature Switzerland AG

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Cite this chapter

Brunaugh, A.D., Moraga-Espinoza, D., Bahamondez-Canas, T., Smyth, H.D.C., Williams, R.O. (2024). Rectal and Vaginal Drug Delivery. In: Essential Pharmaceutics. AAPS Introductions in the Pharmaceutical Sciences, vol 12. Springer, Cham. https://doi.org/10.1007/978-3-031-52520-9_12

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