Abstract
Imagine you need to look inside a living organism. You would have only two options: using invasive techniques or applying tomography. In this non-invasive imaging method, two-dimensional (2D) images of slices, or sections, within an organism are analyzed to determine the three-dimensional (3D) localization of internal objects. These sections can be so thin that the target objects are unobscured by the superposition of over- or underlying structures. The challenge of seeing internal objects that are free of superposition originated in medicine, where such 3D localization is necessary for accurate diagnosis and treatment.
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Frangakis, A.S. (2024). Principles of Tomographic Reconstruction. In: Förster, F., Briegel, A. (eds) Cryo-Electron Tomography. Focus on Structural Biology, vol 11. Springer, Cham. https://doi.org/10.1007/978-3-031-51171-4_2
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DOI: https://doi.org/10.1007/978-3-031-51171-4_2
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