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SiO2-Based Nanomaterials as Antibacterial and Antiviral Agents: Potential Applications

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Nanoparticles in Modern Antimicrobial and Antiviral Applications

Part of the book series: Nanotechnology in the Life Sciences ((NALIS))

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Abstract

SiO2 nanoparticles have emerged as a potential solution for combating bacterial and viral infections due to their unique physicochemical properties. These nanoparticles possess a high surface area-to-volume ratio, allowing them to adsorb onto the surface of bacterial and viral cells and disrupt their membrane integrity. Additionally, SiO2 nanoparticles can generate reactive oxygen species (ROS) upon exposure to light or heat, which can induce oxidative stress and damage to bacterial and viral cells. However, the use of SiO2 nanoparticles as antimicrobial agents also presents certain challenges and risks, such as their potential toxicity to human cells and the environment. In this chapter, we review the latest research work, highlighting the advantages and disadvantages of SiO2 nanoparticles and their potential applications for COVID-19 prevention, detection, and treatment. We also examine the toxicity concerns associated with SiO2 nanoparticles and the need for further research to ensure their safe use. Overall, this chapter aims to provide a comprehensive overview of the current state-of-the-art in SiO2 nanoparticle research for antimicrobial applications, with a focus on COVID-19 prevention and treatment.

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Acknowledgments

KVP acknowledges Fondecyt Regular Project No. 1211118, ANID, and FIT, USS, Chile.

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Authors and Affiliations

  1. Facultad de Ingeniería, Arquitectura y Diseño, University of San Sebastián, Concepción, Chile

    Varaprasad Kokkarachedu

  2. Department of Chemical and Biochemical Engineering, Dongguk University, Seoul, Republic of Korea

    Karthikeyan Chandrasekaran

  3. Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand

    Natarajan Sisubalan

  4. Department of Biomedical Engineering, University of Memphis, Memphis, TN, USA

    Tippabattini Jayaramudu

  5. Department of Microbiology, SRM Institute of Science and Technology, Tiruchirappalli, TN, India

    Arumugam Vijayan

  6. Department of Chemical, Metallurgical & Materials Engineering, Institute of Nano Engineering Research (INER), Tshwane University of Technology, Pretoria West Campus, Pretoria, Republic of South Africa

    Rotimi Sadiku

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  1. Varaprasad Kokkarachedu
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  2. Karthikeyan Chandrasekaran
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  3. Natarajan Sisubalan
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  4. Tippabattini Jayaramudu
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  5. Arumugam Vijayan
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  6. Rotimi Sadiku
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Correspondence to Varaprasad Kokkarachedu .

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Editors and Affiliations

  1. Facultad de Ingeniería Arquitectura y Diseño, University of San Sebastián, Concepción, Chile

    Varaprasad Kokkarachedu

  2. Department of Chemical, Metallurgical and Materials Engineering Institute for Nano Engineering Research (INER), Tshwane University of Technology, Pretoria, South Africa

    Rotimi Sadiku

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Kokkarachedu, V., Chandrasekaran, K., Sisubalan, N., Jayaramudu, T., Vijayan, A., Sadiku, R. (2024). SiO2-Based Nanomaterials as Antibacterial and Antiviral Agents: Potential Applications. In: Kokkarachedu, V., Sadiku, R. (eds) Nanoparticles in Modern Antimicrobial and Antiviral Applications. Nanotechnology in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-031-50093-0_4

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