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Iatrogenic Neurologic Complications

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Clinical Management of Salivary Gland Disorders

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Abstract

The nerve supply to the major salivary glands exists in an overcrowded anatomic area. The head and neck area is replete with a vast cramped neurologic network. Therefore, operating within the limited anatomic confines of the head and neck, not in the immediate vicinity of the major salivary glands, the surgeon may inadvertently injure a neurologic structure as it travels to a salivary gland. Disruption in normal gland function is the end result. Damage to the chorda tympani nerve during stapes surgery will cause a decrease in submandibular and sublingual gland salivary volume. Furthermore, salivary gland surgical procedures that involve the parotid gland may disrupt a nerve’s ability to stimulate the parotid gland (auriculotemporal syndrome) or the paraglandular musculature (facial nerve palsy).

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References

  1. Sajisevi M. Indications for facial nerve monitoring during parotidectomy. Otolaryngol Clin North Am. 2021;54(3):489–96. https://doi.org/10.1016/j.otc.2021.02.001.

    Article  PubMed  Google Scholar 

  2. El Sayed AY, Winters R. Parotidectomy. In: StatPearls. Treasure Island: StatPearls Publishing; 2021.

    Google Scholar 

  3. Nouraei SA, Ismail Y, Ferguson MS, et al. Analysis of complications following surgical treatment of benign parotid disease. ANZ J Surg. 2008;78(3):134–8. https://doi.org/10.1111/j.1445-2197.2007.04388.x.

    Article  PubMed  Google Scholar 

  4. Kawata R, Kinoshita I, Omura S, et al. Risk factors of postoperative facial palsy for benign parotid tumors: outcome of 1,018 patients. Laryngoscope. 2021;131(12):E2857–64. https://doi.org/10.1002/lary.29623.

    Article  PubMed  Google Scholar 

  5. Goomany A, Sood S. Superficial parotidectomy for chronic parotid sialadenitis: a case series and review of the literature. J Laryngol Otol. 2021;135(10):883–6. https://doi.org/10.1017/S0022215121002115.

    Article  CAS  PubMed  Google Scholar 

  6. O’Neill JP, Condron C, Curran A, Walsh A. Lucja Frey—historical relevance and syndrome review. Surgeon. 2008;6(3):178–81. https://doi.org/10.1016/s1479-666x(08)80115-1.

    Article  PubMed  Google Scholar 

  7. Motz KM, Kim YJ. Auriculotemporal syndrome (Frey syndrome). Otolaryngol Clin North Am. 2016;49(2):501–9. https://doi.org/10.1016/j.otc.2015.10.010.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Marchese MR, Bussu F, Settimi S, Scarano E, Almadori G, Galli J. Not only gustatory sweating and flushing: signs and symptoms associated to the Frey syndrome and the role of botulinum toxin A therapy. Head Neck. 2021;43(3):949–55. https://doi.org/10.1002/hed.26561.

    Article  PubMed  Google Scholar 

  9. Sood S, Quraishi MS, Bradley PJ. Frey’s syndrome and parotid surgery. Clin Otolaryngol Allied Sci. 1998;23(4):291–301. https://doi.org/10.1046/j.1365-2273.1998.00154.x.

    Article  CAS  PubMed  Google Scholar 

  10. Farrell ML, Kalnins IK. Frey’s syndrome following parotid surgery. Aust N Z J Surg. 1991;61(4):295–301. https://doi.org/10.1111/j.1445-2197.1991.tb00215.x.

    Article  CAS  PubMed  Google Scholar 

  11. Adedeji TO, Indorewala S, Indorewala A, Nemade G. Stapedotomy and its effect on hearing—our experience with 54 cases. Afr Health Sci. 2016;16(1):276–81. https://doi.org/10.4314/ahs.v16i1.36.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Shea JJ. Symposium: the operation for the mobilization of the stapes in otosclerotic deafness. Laryngoscope. 1956;66:729–84.

    Google Scholar 

  13. Miman MC, Sigirci A, Ozturan O, Karatas E, Erdem T. The effects of the chorda tympani damage on submandibular glands: biometric changes. Auris Nasus Larynx. 2003;30(1):21–4. https://doi.org/10.1016/s0385-8146(02)00027-5.

    Article  PubMed  Google Scholar 

  14. Skoloudik L, Krtickova J, Haviger J, Mejzlik J, Chrobok V. Changes of taste perception after stapes surgery: a prospective cohort study. Eur Arch Otorrinolaringol. 2022;279(1):175–9. https://doi.org/10.1007/s00405-021-06665-0.

    Article  Google Scholar 

  15. Michael P, Raut V. Chorda tympani injury: operative findings and postoperative symptoms. Otolaryngol Head Neck Surg. 2007;136(6):978–81. https://doi.org/10.1016/j.otohns.2006.12.022.

    Article  PubMed  Google Scholar 

  16. Bull TR. Taste and the chorda tympani. J Laryngol Otol. 1965;79:479–93. https://doi.org/10.1017/s0022215100063969.

    Article  CAS  PubMed  Google Scholar 

  17. Yagmur C, Miman MC, Karatas E, Akarcay M, Erdem T, Ozturan O. Effects of the chorda tympani damage on submandibular glands: scintigraphic changes. J Laryngol Otol. 2004;118(2):102–5. https://doi.org/10.1258/002221504772784531.

    Article  CAS  PubMed  Google Scholar 

  18. Dawes C. Salivary flow patterns and the health of hard and soft oral tissues. J Am Dent Assoc. 2008;139 Suppl:18S–24S. https://doi.org/10.14219/jada.archive.2008.0351.

    Article  PubMed  Google Scholar 

  19. Mandel L. Hyposalivation after undergoing stapedectomy. J Am Dent Assoc. 2012;143(1):39–42. https://doi.org/10.14219/jada.archive.2012.0016.

    Article  PubMed  Google Scholar 

  20. Charles-Harris H, Rodriguez B. First bite syndrome: presentation of a patient status-post right carotid endarterectomy. Vasc Endovascular Surg. 2021;55(1):64–8. https://doi.org/10.1177/1538574420954589.

    Article  PubMed  Google Scholar 

  21. Haubrich WS. The first-bite syndrome. Henry Ford Hosp Med J. 1986;34(4):275–8.

    CAS  PubMed  Google Scholar 

  22. Netterville JL, Jackson CG, Miller FR, Wanamaker JR, Glasscock ME. Vagal paraganglioma: a review of 46 patients treated during a 20-year period. Arch Otolaryngol Head Neck Surg. 1998;124(10):1133–40. https://doi.org/10.1001/archotol.124.10.1133.

    Article  CAS  PubMed  Google Scholar 

  23. Linkov G, Morris LG, Shah JP, Kraus DH. First bite syndrome: incidence, risk factors, treatment, and outcomes. Laryngoscope. 2012;122(8):1773–8. https://doi.org/10.1002/lary.23372.

    Article  PubMed  Google Scholar 

  24. Avinçsal MÖ, Hiroshima Y, Shinomiya H, Shinomiya H, Otsuki N, Nibu KI. First bite syndrome—an 11-year experience. Auris Nasus Larynx. 2017;44(3):302–5. https://doi.org/10.1016/j.anl.2016.07.012.

    Article  PubMed  Google Scholar 

  25. Xu V, Gill KS, Goldfarb J, et al. First bite syndrome after parotidectomy: a case series and review of literature. Ear Nose Throat J. 2022;101:663–7.

    Article  PubMed  Google Scholar 

  26. Mandel L, Syrop SB. First-bite syndrome after parapharyngeal surgery for cervical schwannoma. J Am Dent Assoc. 2008;139(11):1480–3. https://doi.org/10.14219/jada.archive.2008.0073.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Oral and Maxillofacial Surgery, Columbia University /New York Presbyterian Hospital, New York, NY, USA

    Louis Mandel

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Correspondence to Louis Mandel .

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Mandel, L. (2024). Iatrogenic Neurologic Complications. In: Clinical Management of Salivary Gland Disorders. Springer, Cham. https://doi.org/10.1007/978-3-031-50012-1_16

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  • DOI: https://doi.org/10.1007/978-3-031-50012-1_16

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-50011-4

  • Online ISBN: 978-3-031-50012-1

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