Abstract
Background: Osteoarthritis is a common and disabling condition; commonly requiring surgical management with total knee arthroplasty (TKA) when conservative measures fail. Although TKA is a well-established and effective management, it is not without its issues, with a significant number of patients experiencing complications and need for complex revision procedures in later years.
Knee joint distraction (KJD) is an emerging technique used to mitigate symptoms of moderate to severe osteoarthritis. Patients who might otherwise be considering high tibial osteotomy (HTO) or TKA may be able to delay arthroplasty and reduce the necessity for multiple increasingly complex revision procedures.
Methods: Many different types of devices have been used for joint distraction. Ankle joint distraction (AJD) has been used to good effect with hinged and static devices. The most established technique for KJD is a spring-loaded static device with results described in 62 patients up to 5 years.
Outcomes: Pain and function scores show improvements at up to 5 years of follow up compared to the natural progression of OA managed with conservative measures. No inferiority was seen in pain and function scores at 1 year compared with HTO, or TKA.
Radiographs demonstrate sustained increases in joint space on follow up. Magnetic resonance imaging (MRI) demonstrates increases in mean cartilage thickness and improvements in the quality of the cartilaginous tissue.
Assessment of cartilage samples and breakdown products indicate varying results depending on markers used and the stage at which the sample was taken. There is some evidence of decreased cartilage breakdown products and increased proteoglycan synthesis following KJD.
Complications include pin-site infection with a small number of deep infections, deep vein thrombosis and pulmonary embolism, device failures and foot drop.
Uncertainties: There is currently no established technique for KJD, although several papers have used similar techniques with good outcomes. There are presently outcomes up to only 5 years of follow up.
Conclusion: Numerous advantageous outcomes have been demonstrated by the early work into KJD. As a last resort before moving to TKA, it appears to be an attractive alternative; however, the uncertainties and potential complications must be considered on an individual basis with further research being necessary before establishing this as a mainstream option.
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References
Cross M, Smith E, Hoy D, et al. The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis. 2014;73(7):1323–30.
Peat G, McCarney R, Croft P. Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care. Ann Rheum Dis. 2001;60(2):91–7.
Culliford DJ, Maskell J, Beard DJ, Murray DW, Price AJ, Arden NK. Temporal trends in hip and knee replacement in the United Kingdom: 1991 to 2006. J Bone Joint Surg (Br). 2010;92(1):130–5.
Zhang Y, Jordan JM. Epidemiology of osteoarthritis. Clin Geriatr Med. 2010;26(3):355–69.
Patel A, Pavlou G, Mújica-Mota RE, Toms AD. The epidemiology of revision total knee and hip arthroplasty in England and Wales: a comparative analysis with projections for the United States. A study using the National Joint Registry dataset. Bone Joint J. 2015;97-B(8):1076–81.
Excellence NIfHaC. Osteoarthritis: care and management Clinical Guideline [CG177]. 2014.
Surgeons AAoO. Treatment of Osteoarthritis of the Knee. 2013.
Kurtz S, Ong K, Lau E, Mowat F, Halpern M. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am. 2007;89(4):780–5.
Nam D, Nunley RM, Barrack RL. Patient dissatisfaction following total knee replacement: a growing concern? Bone Joint J. 2014;96-B(11 Supple A):96–100.
Parvizi J, Nunley RM, Berend KR, et al. High level of residual symptoms in young patients after total knee arthroplasty. Clin Orthop Relat Res. 2014;472(1):133–7.
Kahlenberg CA, Nwachukwu BU, McLawhorn AS, Cross MB, Cornell CN, Padgett DE. Patient satisfaction after Total knee replacement: a systematic review. HSS J. 2018;14(2):192–201.
Evans JT, Walker RW, Evans JP, Blom AW, Sayers A, Whitehouse MR. How long does a knee replacement last? A systematic review and meta-analysis of case series and national registry reports with more than 15 years of follow-up. Lancet. 2019;393(10172):655–63.
Bae DK, Song SJ, Park MJ, Eoh JH, Song JH, Park CH. Twenty-year survival analysis in total knee arthroplasty by a single surgeon. J Arthroplast. 2012;27(7):1297–1304.e1291.
Culliford D, Maskell J, Judge A, et al. Future projections of total hip and knee arthroplasty in the UK: results from the UK clinical practice research datalink. Osteoarthr Cartil. 2015;23(4):594–600.
Kurtz SM, Lau E, Ong K, Zhao K, Kelly M, Bozic KJ. Future young patient demand for primary and revision joint replacement: national projections from 2010 to 2030. Clin Orthop Relat Res. 2009;467(10):2606–12.
Keeney JA, Eunice S, Pashos G, Wright RW, Clohisy JC. What is the evidence for total knee arthroplasty in young patients?: a systematic review of the literature. Clin Orthop Relat Res. 2011;469(2):574–83.
Bayliss LE, Culliford D, Monk AP, et al. The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study. Lancet. 2017;389(10077):1424–30.
Bhandari M, Smith J, Miller LE, Block JE. Clinical and economic burden of revision knee arthroplasty. Clin Med Insights Arthritis Musculoskelet Disord. 2012;5:89–94.
Lee DH, Lee SH, Song EK, Seon JK, Lim HA, Yang HY. Causes and clinical outcomes of revision Total knee arthroplasty. Knee Surg Relat Res. 2017;29(2):104–9.
Ong KL, Lau E, Suggs J, Kurtz SM, Manley MT. Risk of subsequent revision after primary and revision total joint arthroplasty. Clin Orthop Relat Res. 2010;468(11):3070–6.
Judet R, Judet T. The use of a hinge distraction apparatus after arthrolysis and arthroplasty (author's transl). Rev Chir Orthop Reparatrice Appar Mot. 1978;64(5):353–65.
van Valburg AA, van Roermund PM, Lammens J, et al. Can Ilizarov joint distraction delay the need for an arthrodesis of the ankle? A preliminary report. J Bone Joint Surg (Br). 1995;77(5):720–5.
Lafeber F, Veldhuijzen JP, Vanroy JL, Huber-Bruning O, Bijlsma JW. Intermittent hydrostatic compressive force stimulates exclusively the proteoglycan synthesis of osteoarthritic human cartilage. Br J Rheumatol. 1992;31(7):437–42.
Marijnissen AC, Van Roermund PM, Van Melkebeek J, et al. Clinical benefit of joint distraction in the treatment of severe osteoarthritis of the ankle: proof of concept in an open prospective study and in a randomized controlled study. Arthritis Rheum. 2002;46(11):2893–902.
Nguyen MP, Pedersen DR, Gao Y, Saltzman CL, Amendola A. Intermediate-term follow-up after ankle distraction for treatment of end-stage osteoarthritis. J Bone Joint Surg Am. 2015;97(7):590–6.
Rodriguez-Merchan EC. Joint distraction in advanced osteoarthritis of the ankle. Arch Bone Jt Surg. 2017;5(4):208–12.
Spaans AJ, Minnen LPV, Braakenburg A, Mink van der Molen AB. Joint distraction for thumb carpometacarpal osteoarthritis: a feasibility study with 1-year follow-up. J Plast Surg Hand Surg. 2017;51(4):254–8.
Sandvall BK, Cameron TE, Netscher DT, Epstein MJ, Staines KG, Petersen NJ. Basal joint osteoarthritis of the thumb: ligament reconstruction and tendon interposition versus hematoma distraction arthroplasty. J Hand Surg [Am]. 2010;35(12):1968–75.
Gray KV, Meals RA. Hematoma and distraction arthroplasty for thumb basal joint osteoarthritis: minimum 6.5-year follow-up evaluation. J Hand Surg [Am]. 2007;32(1):23–9.
van der Woude JA, Nair SC, Custers RJ, et al. Knee joint distraction compared to Total knee arthroplasty for treatment of end stage osteoarthritis: simulating long-term outcomes and cost-effectiveness. PLoS One. 2016;11(5):e0155524.
Koshino T, Wada S, Ara Y, Saito T. Regeneration of degenerated articular cartilage after high tibial valgus osteotomy for medial compartmental osteoarthritis of the knee. Knee. 2003;10(3):229–36.
Hoemann CD, Tran-Khanh N, Chevrier A, et al. Chondroinduction is the Main cartilage repair response to microfracture and microfracture with BST-CarGel: results as shown by ICRS-II histological scoring and a novel zonal collagen type scoring method of human clinical biopsy specimens. Am J Sports Med. 2015;43(10):2469–80.
Brandt KD. Response of joint structures to inactivity and to reloading after immobilization. Arthritis Rheum. 2003;49(2):267–71.
Vanwanseele B, Lucchinetti E, Stüssi E. The effects of immobilization on the characteristics of articular cartilage: current concepts and future directions. Osteoarthr Cartil. 2002;10(5):408–19.
van Valburg AA, van Roy HL, Lafeber FP, Bijlsma JW. Beneficial effects of intermittent fluid pressure of low physiological magnitude on cartilage and inflammation in osteoarthritis. An in vitro study. J Rheumatol. 1998;25(3):515–20.
Baboolal TG, Mastbergen SC, Jones E, Calder SJ, Lafeber FP, McGonagle D. Synovial fluid hyaluronan mediates MSC attachment to cartilage, a potential novel mechanism contributing to cartilage repair in osteoarthritis using knee joint distraction. Ann Rheum Dis. 2016;75(5):908–15.
Gessmann J, Baecker H, Jettkant B, Muhr G, Seybold D. Direct and indirect loading of the Ilizarov external fixator: the effect on the interfragmentary movements and compressive loads. Strategies Trauma Limb Reconstr. 2011;6(1):27–31.
Saltzman CL, Hillis SL, Stolley MP, Anderson DD, Amendola A. Motion versus fixed distraction of the joint in the treatment of ankle osteoarthritis: a prospective randomized controlled trial. J Bone Joint Surg Am. 2012;94(11):961–70.
Bernstein M, Reidler J, Fragomen A, Rozbruch SR. Ankle distraction arthroplasty: indications, technique, and outcomes. J Am Acad Orthop Surg. 2017;25(2):89–99.
Deie M, Ochi M, Adachi N, Kajiwara R, Kanaya A. A new articulated distraction arthroplasty device for treatment of the osteoarthritic knee joint: a preliminary report. Arthroscopy. 2007;23(8):833–8.
Aly TA, Hafez K, Amin O. Arthrodiatasis for management of knee osteoarthritis. Orthopedics. 2011;34(8):e338–43.
van der Woude JAD, Wiegant K, van Roermund PM, et al. Five-year follow-up of knee joint distraction: clinical benefit and cartilaginous tissue repair in an open uncontrolled prospective study. Cartilage. 2017;8(3):263–71.
van der Woude JAD, Wiegant K, van Heerwaarden RJ, et al. Knee joint distraction compared with high tibial osteotomy: a randomized controlled trial. Knee Surg Sports Traumatol Arthrosc. 2017;25(3):876–86.
Intema F, Van Roermund PM, Marijnissen AC, et al. Tissue structure modification in knee osteoarthritis by use of joint distraction: an open 1-year pilot study. Ann Rheum Dis. 2011;70(8):1441–6.
Wiegant K, van Roermund PM, Intema F, et al. Sustained clinical and structural benefit after joint distraction in the treatment of severe knee osteoarthritis. Osteoarthr Cartil. 2013;21(11):1660–7.
Chen Y, Sun Y, Pan X, Ho K, Li G. Joint distraction attenuates osteoarthritis by reducing secondary inflammation, cartilage degeneration and subchondral bone aberrant change. Osteoarthr Cartil. 2015;23(10):1728–35.
Vincent TL. IL-1 in osteoarthritis: time for a critical review of the literature. F1000Res. 2019:8.
Wang M, Sampson ER, ** H, et al. MMP13 is a critical target gene during the progression of osteoarthritis. Arthritis Res Ther. 2013;15(1):R5.
Besselink NJ, Vincken KL, Bartels LW, et al. Cartilage quality (dGEMRIC index) following knee joint distraction or high Tibial osteotomy. Cartilage. 2020;11(1):19–31.
Jansen MP, Mastbergen SC, van Heerwaarden RJ, et al. Knee joint distraction in regular care for treatment of knee osteoarthritis: a comparison with clinical trial data. PLoS One. 2020;15(1):e0227975.
Takahashi T, Baboolal TG, Lamb J, Hamilton TW, Pandit HG. Is knee joint distraction a viable treatment option for knee OA?-a literature review and meta-analysis. J Knee Surg. 2019;32(8):788–95.
Rutgers M, Bartels LW, Tsuchida AI, et al. dGEMRIC as a tool for measuring changes in cartilage quality following high tibial osteotomy: a feasibility study. Osteoarthr Cartil. 2012;20(10):1134–41.
Ferguson D, Harwood P, Allgar V, et al. The PINS trial: a prospective randomized clinical trial comparing a traditional versus an emollient skincare regimen for the care of pin-sites in patients with circular frames. Bone Joint J. 2021;103-B(2):279–85.
Williams RL, Khan W, Roberts-Huntleigh N, Morgan-Jones R. Total knee arthroplasty in patients with prior adjacent multi-organism osteomyelitis. Acta Orthop Belg. 2018;84(2):184–91.
van der Woude JA, van Heerwaarden RJ, Spruijt S, et al. Six weeks of continuous joint distraction appears sufficient for clinical benefit and cartilaginous tissue repair in the treatment of knee osteoarthritis. Knee. 2016;23(5):785–91.
Lim JB, Chi CH, Lo LE, et al. Gender difference in outcome after total knee replacement. J Orthop Surg (Hong Kong). 2015;23(2):194–7.
Novicoff WM, Saleh KJ. Examining sex and gender disparities in total joint arthroplasty. Clin Orthop Relat Res. 2011;469(7):1824–8.
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Lineham, B., Harwood, P., Pandit, H.G. (2023). Knee Distraction for Managing Knee Osteoarthritis. In: Deshmukh, A.J., Shabani, B.H., Waldstein, W., Oni, J.K. (eds) Surgical Management of Knee Arthritis. Springer, Cham. https://doi.org/10.1007/978-3-031-47929-8_20
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