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Advanced Optical Nanosensors

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Handbook of Nanosensors

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Abstract

Advanced optical nanosensors are sensors that convert the detectable interaction changes between molecules with analytes into analytically useful information based on light intensity. The radiation-sample interaction is measured for changes in certain optical properties in correlation with the analyte concentration. Also, a variety of optical principles can be applied to optical sensors (absorbance, reflection, luminescence, fluorescence), covering different regions of the spectrum (UV, visible, near-infrared (NIR)). This allows light intensity measurements plus other properties such as lifetime, refractive index, scattering, diffraction, and polarization. Additionally, the user often expects additional sensor characteristics, for instance, a sufficiently high signal-to-noise ratio, quick response time, low detection limit, high sensitivity, low cost, and the possibility of online and in-situ applications. This chapter aims to provide details of the principle and mechanism of specific optical nanosensors (viz., luminescent, surface plasmon resonance (SPR), and quantum dots), the preparation of certain advanced nanosensors (viz., nano-cellulose, silver nanoparticles, and carbon-based), and their current bionanotechnological applications. Optical nanosensors are an emerging technique for personalized health monitoring and could revolutionize how diseases are diagnosed and treated in the future. The use of optical nanosensors in environmental monitoring and food quality analysis is also prominent.

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Abbreviations

AKD:

Alkyl Ketene Dimer

AMX:

Amoxicillin Antibiotics

Au/AgNPs:

Gold/Silver Nanoparticles

BPEI:

Branched-Polyethylenimine

BPT:

Benzo[α]pyrene Tetrol

CD:

Carbon Dot

CEF:

Chelation-Enhanced Fluorescence

CEQ:

Chelation-Enhanced Quenching

CFP:

Cyan Fluorescent Protein

CL/FL/PL:

Chemiluminescence/Fluorescence/Photoluminescence

CNF:

Cellulose Nanofibers

CPW:

Coplanar Waveguide

CQDs/GQDs:

Carbon Quantum Dots/Graphene Quantum Dots

CRP:

C-reactive Protein

DFT:

Density Functional Theory

DNA/RNA:

Deoxyribonucleic acid/Ribonucleic acid

FAR:

Fused Aromatic Ring

FMNP:

Fluorescent Magnetic Nanoprobes

FRET:

Fluorescence Resonance Energy Transfer

GO:

Graphene Oxide

HEC:

Hydroxyethyl Cellulose

HOMO:

Highest Occupied Molecular Orbital

HPLC:

High-Performance Liquid Chromatography

HPMC:

Hydroxypropyl Methylcellulose

IFE:

Internal Filtering Effect

LOD:

Limit of Detection

LSPR:

Localized Surface Plasmon Resonance

LUMO:

Lowest Unoccupied Molecular Orbital

MB:

Molecular Beacon

MC:

Methyl Cellulose

MG:

Malachite Green

mRNAs:

Messenger Ribonucleic Acid

MSCs:

Mesenchymal Stem Cells

NCDs:

Amino-functionalized Carbon Dots

NIR:

Near Infrared

NR:

Neutral Red

PFMS:

Pyrene Functionalized Mesoporous Silica

Ppb:

Part Per Billion

QCM:

Quartz Crystal Microbalance

QY/PLQY:

Quantum Yield/Photoluminescence Quantum Yield

RF:

Radiofrequency

SERS:

Surface Enhanced Raman Spectroscopy

SPR:

Surface Plasmon Resonance

ssDNA:

Single-Stranded DNA

TLC:

Thin Layer Chromatography

TMT-AuNPs:

Trithiocyanuric Acid Modified Gold Nanoparticles

UCNP:

Upconversion Nanoparticles

UV:

Ultraviolet

UV-Vis:

Ultraviolet Visible Spectroscopy

VOC:

Volatile Organic Compound

YFP:

Yellow Fluorescent Protein

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Acknowledgments

The authors highly acknowledged the grant received by Universiti Teknologi Malaysia (UTM) with the vote no. Q.J130000.2654.18 J18.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Universiti Teknologi Malaysia, Johor Bahru, Malaysia

    Juan Matmin, Fuad Mohamad & Roswanira Abdul Wahab

  2. Center for Research and Development, Asia Metropolitan University, Johor Bahru, Malaysia

    Mohd Hayrie Mohd Hatta

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  1. Juan Matmin
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  2. Fuad Mohamad
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  3. Roswanira Abdul Wahab
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  4. Mohd Hayrie Mohd Hatta
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Corresponding author

Correspondence to Juan Matmin .

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Editors and Affiliations

  1. Chemistry Department, Al-Azhar University, Assiut, Egypt

    Gomaa A. M. Ali

  2. Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, Pekan, Malaysia

    Kwok Feng Chong

  3. President at EMC3 LLC, West Hartford, CT, CT, USA

    Abdel Salam H. Makhlouf

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Matmin, J., Mohamad, F., Wahab, R.A., Hatta, M.H.M. (2024). Advanced Optical Nanosensors. In: Ali, G.A.M., Chong, K.F., Makhlouf, A.S.H. (eds) Handbook of Nanosensors. Springer, Cham. https://doi.org/10.1007/978-3-031-47180-3_30

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