Abstract
A genetic disorder is a disease caused in whole or in part by a change in the DNA sequence away from the normal sequence. These are categorised as monogenic, multifactorial, and chromosomal disorders. This chapter discusses single-gene, sex-linked, mitochondrial, and multifactorial inheritance patterns and briefly deals with disorders of genetic origin.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Bibliography
Maitra A. Genetic and pediatric diseases. In: Kumar V, Abbas AK, Aster JC, editors. Robbins basic pathology. 10th ed. Philadelphia: Elsevier; 2018. p. 243–95.
National Research Council (US) Committee on Developmental Toxicology. Scientific frontiers in developmental toxicology and risk assessment. Washington (DC): National Academies Press (US); 2000. 2, Developmental defects and their causes. https://www.ncbi.nlm.nih.gov/books/NBK225664/
Simon Herrington C. Muir’s textbook of pathology. 15th ed. Clinical Genetics; 2014. p. 31–48.
Tobias E, Connor M, Fergusson-Smith M. Essential Medical Genetics. 6th ed. Oxford: Wiley-Blackwell; 2011.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG
About this chapter
Cite this chapter
Prabhu, S.R. (2023). Genetic and Developmental Pathology. In: Textbook of General Pathology for Dental Students. Springer, Cham. https://doi.org/10.1007/978-3-031-31244-1_8
Download citation
DOI: https://doi.org/10.1007/978-3-031-31244-1_8
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-031-31243-4
Online ISBN: 978-3-031-31244-1
eBook Packages: MedicineMedicine (R0)