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Aging of the Vasculature

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Cardiovascular Disease in the Elderly

Part of the book series: Contemporary Cardiology ((CONCARD))

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Abstract

Vascular disease and its consequences remain the most common causes of mortality and significant lifelong disability in developed, and most develo**, countries. Age is the most potent risk factor for the responsible vascular changes and although these are in part dependent on the “quality of the arterial tissue” we inherit, their trajectory can be impacted by the environment our vessels are exposed to. This chapter will review the molecular, cellular, structural, and functional changes associated with aging, the impact of these changes on cardiovascular outcomes, and lifestyle and pharmacologic interventions designed to modify them.

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Authors and Affiliations

  1. Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Thorsten M. Leucker & Gary Gerstenblith

  2. Divison of Cardiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA

    Joseph Goldenberg

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  2. Joseph Goldenberg
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Correspondence to Thorsten M. Leucker .

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  1. School of Medicine, Johns Hopkins University, Baltimore, MD, USA

    Thorsten M. Leucker

  2. School of Medicine, Johns Hopkins University, Baltimore, MD, USA

    Gary Gerstenblith

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Leucker, T.M., Goldenberg, J., Gerstenblith, G. (2023). Aging of the Vasculature. In: Leucker, T.M., Gerstenblith, G. (eds) Cardiovascular Disease in the Elderly. Contemporary Cardiology. Humana, Cham. https://doi.org/10.1007/978-3-031-16594-8_4

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