Pilocytic Astrocytoma (WHO Grade I)

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NeuroRadiosurgery: Case Review Atlas

Abstract

A 9-year-old boy, who had prior surgery for pilocytic astrocytoma 3 months ago, presented asymptomatic. He was treated with adjunctive; Linac-based SRS for mixed cystic-solid, post-surgical residual, suprasellar pilocytic astrocytoma (WHO Grade I). Only the solid tumor component was targeted. The target volume of 9.1 cc received a marginal dose of 10.5 Gy normalized to 70% isodose line. The optic chiasm received a maximum dose of 8.1 Gy. Serial post-SRS follow-up MRIs showed a decrease in size of both the solid and cystic tumor components. At last clinical follow-up (60 months post-SRS), the patient remained asymptomatic and neurologically intact.

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Further Reading

  • Abdelaziz OS. Radiosurgery in neurosurgical practice III: stereotactic radiosurgery for glial brain tumors. Neurosurg Q. 2000;10(2):126–30. https://www.researchgate.net/publication/286618856.

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  • Hadjjpanayis CG, Kondziolka D, Gardner P, et al. Stereotactic radiosurgery for pilocytic astrocytomas when multimodal therapy is necessary. J Neurosurg. 2002;97(1):56–64.

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  • Lizarraga KJ, Gorgulho A, Lee SP, et al. Stereotactic radiation therapy for progressive residual pilocytic astrocytomas. J Neurooncol. 2012;109:129–35.

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  • Sager O, Dincoglan F, Demiral S, et al. Concise review of radiosurgery for contemporary management of pilocytic astrocytomas in children and adults. World J Exp Med. 2022;12(3):36–43.

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Correspondence to Osama S. Abdelaziz .

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Abdelaziz, O.S., De Salles, A.A.F. (2023). Pilocytic Astrocytoma (WHO Grade I). In: NeuroRadiosurgery: Case Review Atlas. Springer, Cham. https://doi.org/10.1007/978-3-031-16199-5_44

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  • DOI: https://doi.org/10.1007/978-3-031-16199-5_44

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-16198-8

  • Online ISBN: 978-3-031-16199-5

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