Cerebro-Cerebellar Networks

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Essentials of Cerebellum and Cerebellar Disorders

Abstract

Considering the cerebellum an independent structure devoted mainly to motor control functions, neuroscience research has, until now, considerably neglected the importance of the cerebellar’s contribution to non-motor functions. In fact, as the cerebellar is anatomo-functionally connected to different large-scale networks in the neocortex, including frontal and parietal regions typically involved in high-order cognitive processing, there is strong evidence to suggest its primary role lay beyond its motor control function. Histologically, the cerebellum contains about 50 billion neurons—roughly half of the total number of neurons in the whole brain, and this impressive order of magnitude supports extremely powerful mechanisms for processing information. The definition of input–output organization between the cerebellum and cerebral cortex helps to clarify the role of the cerebellum in higher cognitive functions. Indeed, these connections provide the means through which association areas and the cerebellum may influence each other’s operations.

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Correspondence to Iolanda Pisotta .

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Pisotta, I., Molinari, M. (2023). Cerebro-Cerebellar Networks. In: Gruol, D.L., Koibuchi, N., Manto, M., Molinari, M., Schmahmann, J.D., Shen, Y. (eds) Essentials of Cerebellum and Cerebellar Disorders. Springer, Cham. https://doi.org/10.1007/978-3-031-15070-8_55

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