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Two-Dimensional vs. Scalar Control of Blood Glucose Level in Diabetic Patients

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Information Technology in Biomedicine (ITIB 2022)

Part of the book series: Advances in Intelligent Systems and Computing ((AISC,volume 1429))

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Abstract

Closed-loop controllers for insulin pumps have been on the market for some time. It has been shown that modified PID or MPC control algorithms are best suited for artificial pancreas. However, due to nonnegative control values only and relatively slow dynamics of the response to insulin input, they are not well equipped to deal with hypoglycemia induced by a physical effort. This paper is focused on that aspect of blood glucose control. Two alternative solutions are proposed and compared. The first one is based on feedforward, with additional information about future physical effort entered by the user. The second approach uses an additional control in the form of glucagon. Simulation is run for a fixed scenario of three meals and additional physical effort that affects the insulin-glucose system for a cohort of virtual patients, for whom model parameters were sampled. Performance of control systems is evaluated with several quality indicators.

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Acknowledgement

This work was supported by the SUT internal grant for young researchers (AW) and the SUT internal grant 02/040/BK_21/1022.

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Authors and Affiliations

  1. Department of Systems Biology and Engineering, Silesian University of Technology, ul. Akademicka 16, 44-100, Gliwice, Poland

    Jarosław Śmieja & Artur Wyciślok

Authors
  1. Jarosław Śmieja
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  2. Artur Wyciślok
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Corresponding author

Correspondence to Artur Wyciślok .

Editor information

Editors and Affiliations

  1. Faculty of Biomedical Engineering, Silesian University of Technology, Gliwice, Poland

    Ewa Pietka

  2. Faculty of Biomedical Engineering, Silesian University of Technology, Gliwice, Poland

    Pawel Badura

  3. Faculty of Biomedical Engineering, Silesian University of Technology, Gliwice, Poland

    Jacek Kawa

  4. Faculty of Biomedical Engineering, Silesian University of Technology, Gliwice, Poland

    Wojciech Wieclawek

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Śmieja, J., Wyciślok, A. (2022). Two-Dimensional vs. Scalar Control of Blood Glucose Level in Diabetic Patients. In: Pietka, E., Badura, P., Kawa, J., Wieclawek, W. (eds) Information Technology in Biomedicine. ITIB 2022. Advances in Intelligent Systems and Computing, vol 1429. Springer, Cham. https://doi.org/10.1007/978-3-031-09135-3_43

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