SpringerLink
Log in

Endocrine-Disrupting Compounds in Water Environment: Analytics and Impact on Living Organisms

  • Reference work entry
  • First Online:
Handbook of Bioanalytics

  • 1001 Accesses

Abstract

Endocrine-disrupting compounds (EDCs) are a wide group of compounds with a harmful effect on living organisms, including humans. Therefore, the presence of EDCs such as pharmaceuticals and personal care products (PPCPs), pesticides, antiseptics, miscellaneous industrial chemicals, and their by-products in water is of concern. Their presence in aquatic bodies is associated mainly with incomplete removal by conventional water and wastewater treatment. This chapter presents the occurrence of EDCs in different aqueous environments, namely, municipal wastewaters, landfill leachate, and groundwater, and their impact on living organisms. This chapter concerns on legal regulation of endocrine-disrupting compounds, sources, and pathways of migration of these compounds in the environment. Additionally, some analytical methods used to determine EDCs in wastewaters, leachate, and groundwater and analytical problems related to assaying their presence in environmental samples were discussed. Finally, one of the ways of determining the potential environmental risk with the occurrence of endocrine-disrupting compounds to water ecosystems (fish, invertebrates, algae, and cyanobacteria) was depicted.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 849.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 949.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Similar content being viewed by others

Reference

  1. Stuart, M., Lapworth, D., Crane, E., & Hart, A. (2012). Review of risk from potential emerging contaminants in UK groundwater. Science of the Total Environment, 416, 1–21.

    Article  CAS  PubMed  Google Scholar 

  2. American Water Works Association. https://www.awwa.org/Portals/0/files/publications/documents/2017SMWWLookInside.pdf (31.05.2019).

  3. Basile, T., Petrella, A., Petrella, M., Boghetich, G., Petruzzelli, V., Colasuonno, S., & Petruzzelli, D. (2011). Review of endocrine-disrupting-compound removal technologies in water and wastewater treatment plants: An EU perspective. Industrial and Engineering Chemistry Research, 50, 8389–8401.

    Article  CAS  Google Scholar 

  4. Directive 2008/105/EC of the European Parliament and of the Council of 16 December 2008 on environmental quality standards in the field of water policy, amending and subsequently repealing Council Directives 82/176/EEC, 83/513/EEC, 84/156/EEC, 84/491/EEC, 86/280/EEC and amending Directive 2000/60/EC of the European Parliament and of the Council (2008).

    Google Scholar 

  5. Directive 2013/39/EU of the European Parliament and of the Council of 12 August 2013 amending Directives 2000/60/EC and 2008/105/EC as regards priority substances in the field of water policy (2013).

    Google Scholar 

  6. Commission Implementing Decision (EU) 2015/495 of 20 March 2015 establishing a watch list of substances for the purposes of Union-wide monitoring in water policy pursuant to Directive 2008/105 / EC of the European Parliament and of the Council (2015).

    Google Scholar 

  7. Directive 2000/60/EC of the European Parliament and of the Council of 23 October 2000 establishing a framework for Community action in the field of water policy (2000).

    Google Scholar 

  8. Commission Regulation (EU) No 358/2014 of 9 April 2014 amending Annexes II and V to Regulation (EC) No 1223/2009 of the European Parliament and of the Council on cosmetic products (2014).

    Google Scholar 

  9. Sobek, A., Bejgarn, S., RudĂ©n, C., Molander, L., & Breitholtz, M. (2013). In the shadow of the cosmetic directive — inconsistencies in EU environmental hazard classification requirements for UV-filter. Science of the Total Environment, 461–462, 706–711.

    Article  PubMed  CAS  Google Scholar 

  10. Katz, T. M., Miller, J. H., & Hebert, A. A. (2008). Insect repellents: Historical perspectives and new developments. Journal of the American Academy of Dermatology, 58, 865–871.

    Article  PubMed  Google Scholar 

  11. Commission Directive 2010/51/EU of 11 August 2010 amending Directive 98/8/EC of the European Parliament and of the Council to include N,N-diethyl-meta-toluamide as an active substance in Annex I thereto (2010).

    Google Scholar 

  12. OSPAR. Commission, Hazardous Substances Series, Octylphenol (2003).

    Google Scholar 

  13. Commission Directive 2011/8/EU of 28 January 2011amending Directive 2002/72/EC as regards the restriction of use of Bisphenol A in plastic infant feeding bottles (2011).

    Google Scholar 

  14. Commission Regulation (EU) No 10/2011 of 14 January 2011 on plastic materials and articles intended to come into contact with food (2011).

    Google Scholar 

  15. European Food Safety Authority (EFSA), Gundert-Remy, U., Bodin, J., Bosetti, C., FitzGerald, R., Hanberg, A., Hass, U., Hooijmans, C., Rooney, A. A., Rousselle, C., van Loveren, H., Wölfle, D., Barizzone, F., Croera, C., Putzu, C., & Castoldi, A. F. (2017). Bisphenol A (BPA) hazard assessment protocol. EFSA Supporting Publication, 14.

    Google Scholar 

  16. Ordinance of the Minister of Economy of 30 January 2015 amending the ordinance on essential requirements for toys, Journal of Laws of 2015, item 198 (2015).

    Google Scholar 

  17. Lapworth, D. J., Baran, N., Stuart, M. E., & Ward, R. S. (2012). Emerging organic contaminants in groundwater: A review of sources, fate and occurrence. Environmental Pollution, 163, 287–303.

    Article  CAS  PubMed  Google Scholar 

  18. Kotowska, U., Kapelewska, J., & Sturgulewska, J. (2014). Determination of phenols and pharmaceuticals in municipal wastewaters from Polish treatment plants by ultrasound-assisted emulsification–microextraction followed by GC–MS. Environmental Science and Pollution Research, 21, 660–673.

    Article  CAS  PubMed  Google Scholar 

  19. Kapelewska, J., Kotowska, U., KarpiƄska, J., Kowalczuk, D., Arciszewska, A., & ƚwirydo, A. (2018). Occurrence, removal, mass loading and environmental risk assessment of emerging organic contaminants in leachates, groundwaters and wastewaters. Microchemical Journal, 137, 292–301.

    Article  CAS  Google Scholar 

  20. Kapelewska, J., Kotowska, U., KarpiƄska, J., Astel, A., ZieliƄski, P., Suchta, J., & Algrzym, K. (2019). Water pollution indicators and chemometric expertise for the assessment of the impact of municipal solid waste landfills on groundwater located in their area. Chemical Engineering Journal, 359, 790–800.

    Article  CAS  Google Scholar 

  21. Tsalbouris, A., Kalogiouri, N. P., & Samanidou, V. F. (2021). Recent advances in miniaturized microextraction techniques for the determination of bisphenols in environmental samples: An overview of the last two decades. Current Analytical Chemistry, 17(4), 478–494.

    Article  CAS  Google Scholar 

  22. Salgueiro-Gonzales, N., Muniategui-Lorenzo, S., Lopez-Mahia, P., & Prada-Rodriguez, D. (2017). Trends in analytical methodologies for the determination of alkylphenols and bisphenol A in water samples. Analytica Chimica Acta, 962, 1–14.

    Article  CAS  Google Scholar 

  23. Mansour, F. R., & Danielson, N. D. (2017). Solidification of floating organic droplet in dispersive liquid-liquid microextraction as a green analytical tool. Talanta, 170, 22–35.

    Article  CAS  PubMed  Google Scholar 

  24. Sadutto, D., & Picó, Y. (2020). Sample preparation to determine pharmaceutical and personal care products in an all-water matrix: Solid phase extraction. Molecules, 25(21), 5204–5225.

    Article  CAS  PubMed Central  Google Scholar 

  25. Wang, X., Huang, P., Ma, X., Du, X., & Lu, X. (2019). Enhanced in-out-tube solid-phase microextraction by molecularly imprinted polymers-coated capillary followed by HPLC for Endocrine Disrupting Chemicals analysis. Talanta, 194, 7–13.

    Article  CAS  PubMed  Google Scholar 

  26. Ghorbani, M., Aghamohammadhassan, M., Chamsaz, M., Akhlaghi, H., & Pedramrad, T. (2019). Dispersive solid phase microextraction. TrAC, Trends in Analytical Chemistry, 118, 793–809.

    Article  CAS  Google Scholar 

  27. Čelić, M., FarrĂ©, M., Lopez de Alda, M., Perez, S., BarcelĂł, D., & Petrović, M. (2017). Environment analysis: Emerging pollutants, chapter 15. In S. Fanali, P. R. Haddad, C. Poole, & M.-L. Riekkola (Eds.), Liquid chromatography applications (Vol. 2, pp. 451–477). Elsevier. eBook ISBN: 9780128093443.

    Chapter  Google Scholar 

  28. Konieczka, P., Wolska, L., & Namieƛnik, J. (2010). Quality problems in determination of organic compounds in environmental samples, such as PAHs and PCBs. TrAC Trends in Analytical Chemistry, 29, 706–717.

    Article  CAS  Google Scholar 

  29. AgĂŒera, A., MartĂ­nez Bueno, M. J., & FernĂĄndez-Alba, A. R. (2013). New trends in the analytical determination of emerging contaminants and their transformation products in environmental waters. Environmental Science and Pollution Research, 20, 3496–3515.

    Article  PubMed  CAS  Google Scholar 

  30. KudƂak, B., & Namieƛnik, J. (2008). Environmental fate of endocrine disrupting compounds—analytical problems and challenges. Critical Reviews in Analytical Chemistry, 38, 242–258.

    Article  CAS  Google Scholar 

  31. Naidu, R., Arias Espana, V. A., Liu, Y., & Jit, J. (2016). Emerging contaminants in the environment: Risk-based analysis for better management. Chemosphere, 154, 350–357.

    Article  CAS  PubMed  Google Scholar 

  32. dos Santos Freitas, L., Bertrand Campos de AraĂșjo, M., Goreti Rodrigues Vale, M., & CaramĂŁo, E. B. (2004). Application of activated carbon in the characterization of nitrogen compounds and phthalates in a landfill leachate. Microchemical Journal, 78, 61–64.

    Article  CAS  Google Scholar 

  33. Öman, C. B., & Junestedt, C. (2008). Chemical characterization of landfill leachates – 400 parameters and compounds. Waste Management, 28, 1876–1891.

    Article  PubMed  Google Scholar 

  34. Wowkonowicz, P., & KijeƄska, M. (2017). Phthalate release in leachate from municipal landfills of central Poland. PLoS One, 12, e0174986.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  35. Eysseric, E., Beaudry, F., Gagnon, C., & Segura, P. A. (2021). Non-target screening of trace organic contaminants in surface waters by a multi-tool approach based on combinatorial analysis of tandem mass spectra and open access databases. Talanta, 230, 122293–122302.

    Article  CAS  PubMed  Google Scholar 

  36. Ternes, T. A., Joss, A., & Siegrist, H. (2004). Peer reviewed: Scrutinizing pharmaceuticals and personal care products in wastewater treatment. Environmental Science & Technology, 38, 392A–399A.

    Article  CAS  Google Scholar 

  37. García-Córcoles, M. T., Rodríguez-Gómez, R., de Alarcón-Gómez, B., Çipa, M., Martín-Pozo, L., Kauffmann, J.-M., & Zafra-Gómez, A. (2019). Chromatographic methods for the determination of emerging contaminants in natural water and wastewater samples: A review. Critical Reviews in Analytical Chemistry, 49, 160–186.

    Article  PubMed  CAS  Google Scholar 

  38. Tran, N. H., Reinhard, M., & Gin, K. Y.-H. (2018). Occurrence and fate of emerging contaminants in municipal wastewater treatment plants from different geographical regions-a review. Water Research, 133, 182–207.

    Article  CAS  PubMed  Google Scholar 

  39. Grassi, M., Rizzo, L., & Farina, A. (2013). Endocrine disruptors compounds, pharmaceuticals and personal care products in urban wastewater: Implications for agricultural reuse and their removal by adsorption process. Environmental Science and Pollution Research, 20, 3616–3628.

    Article  CAS  PubMed  Google Scholar 

  40. Tsui, M. M. P., Leung, H. W., Lam, P. K. S., & Murphy, M. B. (2014). Seasonal occurrence, removal efficiencies and preliminary risk assessment of multiple classes of organic UV filters in wastewater treatment plants. Water Research, 53, 58–67.

    Article  CAS  PubMed  Google Scholar 

  41. Tran, N. H., Urase, T., Ngo, H. H., Hu, J., & Ong, S. L. (2013). Insight into metabolic and cometabolic activities of autotrophic and heterotrophic microorganisms in the biodegradation of emerging trace organic contaminants. Bioresource Technology, 146, 721–731.

    Article  CAS  PubMed  Google Scholar 

  42. Suarez, S., Lema, J. M., & Omil, F. (2010). Removal of Pharmaceutical and Personal Care Products (PPCPs) under nitrifying and denitrifying conditions. Water Research, 44, 3214–3224.

    Article  CAS  PubMed  Google Scholar 

  43. Olasupo, A., Bukhari, F., & Suah, M. (2021). Recent advances in removal of pharmaceuticals and endocrine disrupting compounds in the aquatic system: A case of polymer inclusion membranes. Journal of Hazardous Materials, 406, 124317. https://doi.org/10.1016/j.hazmat.2020.124317

    Article  CAS  PubMed  Google Scholar 

  44. Fudala-Ksiazek, S., Pierpaoli, M., & Luczkiewicz, A. (2017). Fate and significance of phthalates and bisphenol A in liquid by-products generated during municipal solid waste mechanical-biological pre-treatment and disposal. Waste Management, 64, 28–38.

    Article  CAS  PubMed  Google Scholar 

  45. Andrews, W. J., Masoner, J. R., & Cozzarelli, I. M. (2012). Emerging contaminants at a closed and an operating landfill in Oklahoma. Ground Water Monitoring & Remediation, 32, 120–130.

    Article  CAS  Google Scholar 

  46. Masoner, J. R., Kolpin, D. W., Furlong, E. T., Cozzarelli, I. M., Gray, J. L., & Schwab, E. A. (2014). Contaminants of emerging concern in fresh leachate from landfills in the conterminous United States. Environmental Science: Processes & Impacts, 16, 2335–2354.

    CAS  Google Scholar 

  47. Barnes, K. K., Christenson, S. C., Kolpin, D. W., Focazio, M. J., Furlong, E. T., Zaugg, S. D., Meyer, M. T., & Barber, L. B. (2004). Pharmaceuticals and other organic waste water contaminants within a leachate plume downgradient of a municipal landfill. Ground Water Monitoring & Remediation, 24, 119–126.

    Article  CAS  Google Scholar 

  48. Kapelewska, J., Kotowska, U., & Wiƛniewska, K. (2016). Determination of personal care products and hormones in leachate and groundwater from Polish MSW landfills by ultrasound-assisted emulsification microextraction and GC-MS. Environmental Science and Pollution Research, 23, 1642–1652.

    Article  CAS  PubMed  Google Scholar 

  49. Endocrine Disrupting Chemicals and Biomarkers, https://www.alpco.com/endocrine-disrupting-chemicals (31.05.2019).

  50. Esteban, S., Gorga, M., Petrovic, M., González-Alonso, S., Barceló, D., & Valcárcel, Y. (2014). Analysis and occurrence of endocrine-disrupting compounds and estrogenic activity in the surface waters of Central Spain. Sci. Total Environ., 466–467, 939–951.

    Article  PubMed  CAS  Google Scholar 

  51. Molins-Delgado, D., Díaz-Cruz, M. S., & Barceló, D. (2016). Ecological risk assessment associated to the removal of endocrine-disrupting parabens and benzophenone-4 in wastewater treatment. Journal of Hazardous Materials, 310, 143–151.

    Article  CAS  PubMed  Google Scholar 

  52. Braun, J. M., & Hauser, R. (2011). Bisphenol A and childrenÊŒs health. Current Opinion in Pediatrics, 23, 233–239.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  53. Vandenberg, L. N., Hunt, P. A., Myers, J. P., & Vom Saal, F. S. (2013). Human exposures to bisphenol A: Mismatches between data and assumptions. Reviews on Environmental Health, 28, 37–58.

    Article  CAS  PubMed  Google Scholar 

  54. EMA, Guideline on the environmental risk assessment of medicinal products for human use, CPMP/SWP/4447/00 draft, European Medicines Agency (2005).

    Google Scholar 

  55. Hernando, M., Mezcua, M., Fernandezalba, A., & Barcelo, D. (2006). Environmental risk assessment of pharmaceutical residues in wastewater effluents, surface waters and sediments. Talanta, 69, 334–342.

    Article  CAS  PubMed  Google Scholar 

  56. Backhaus, T., & Faust, M. (2012). Predictive environmental risk assessment of chemical mixtures: A conceptual framework. Environmental Science & Technology, 46, 2564–2573.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Analytical and Inorganic Chemistry, Faculty of Chemistry, University of Bialystok, Bialystok, Poland

    Justyna Kapelewska, Urszula Kotowska & Joanna KarpiƄska

Authors
  1. Justyna Kapelewska
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Urszula Kotowska
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Joanna KarpiƄska
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Justyna Kapelewska .

Editor information

Editors and Affiliations

  1. Environmental Chemistry and Bioanalytics, Nicolaus Copernicus University, Torun, Poland

    BogusƂaw Buszewski

  2. Department of Inorganic Chemistry, Analytical Chemistry and Electrochemistry, Faculty of Chemistry, Silesian University of Technology, Gliwice, Poland

    Irena Baranowska

Section Editor information

  1. Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada

    Tadeusz GĂłrecki

Rights and permissions

Reprints and permissions

Copyright information

© 2022 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Kapelewska, J., Kotowska, U., KarpiƄska, J. (2022). Endocrine-Disrupting Compounds in Water Environment: Analytics and Impact on Living Organisms. In: Buszewski, B., Baranowska, I. (eds) Handbook of Bioanalytics. Springer, Cham. https://doi.org/10.1007/978-3-030-95660-8_43

Download citation

Publish with us

Policies and ethics

Search

Navigation