Abstract
This article shows the results of studies carried out in a sheep-breeding farm, where there was a pronounced problem of ketosis and hepatopathy. A new fodder hepatoprotector heprasan-Neo was chosen as a drug that has a targeted hapatoprotective effect on liver cells. This tool combines the biologically active properties of herbal components traditional for hepatoprotective preparations and antioxidants. As a result of the drug use continuously for 21 days, the mortality rate on the farm has decreased. In the groups of animals formed for the control of the experiment, the restoration of the protein-synthetic function of the liver, indicators of lipid, carbohydrate and pigment metabolism was reliably determined by laboratory tests. The new drug due to plant flavonoid components had a positive effect on the antioxidant defense system of the body of southern beef sheep, which was objectively confirmed by a decrease in the level of lipid peroxidation products during the use of the drug. A detoxification effect was also observed, expressed in a decrease in medium mass molecules (MMM) in experimental animals by 2–5%. From the obtained results it can be concluded that the new hepatoprotector heprasan-Neo is effective in the pathogenetic therapy of metabolic pathologies of the liver of the dystrophic nature.
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Abramov, A., Semenenko, M., Semenenko, K., Kuzminova, E., Osepchuk, D., Rogaleva, E. (2022). Efficiency of the Drug Heprasan-Neo in the Pathogenetic Therapy of Fatty Liver Disease in Sheep. In: Muratov, A., Ignateva, S. (eds) Fundamental and Applied Scientific Research in the Development of Agriculture in the Far East (AFE-2021). AFE 2021. Lecture Notes in Networks and Systems, vol 354. Springer, Cham. https://doi.org/10.1007/978-3-030-91405-9_4
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