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Optical Quality Resorbable Calcium-Phosphate Glasses for Biophotonic Applications

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Ceramics, Glass and Glass-Ceramics

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Abstract

Recently developed calcium-phosphate glass formulations are proposed in this chapter as a new class of materials for biomedical optics and photonics. The glasses have been designed and carefully prepared in our laboratory to be dissolvable in biological fluids while being optically transparent, mechanically reliable both in dry and humid environments, and suitable for both preform extrusion and fiber drawing. Optical fibers have been drawn from these glasses using our custom-made induction heated drawing tower and showed attenuation loss values from one to two orders of magnitude lower than the counterpart polymeric-based bioresorbable devices reported in literature. In addition, the optical fibers have been implanted in living rats for several weeks and no clinical signs of any adverse effect have been found. Results on the inscription and characterization of different types of fiber Bragg grating-based optical filters will be also shown, together with the demonstration of the suitability of the above-mentioned bioresorbable optical fibers for time-domain diffuse optical spectroscopy.

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Authors and Affiliations

  1. DISAT—Politecnico di Torino and RU INSTM, 10129, Torino, Italy

    Diego Pugliese & Davide Janner

  2. LINKS Foundation—Leading Innovation and Knowledge for Society, 10138, Torino, Italy

    Nadia Giovanna Boetti

  3. DIA—Università di Parma and RU INSTM, 43124, Parma, Italy

    Daniel Milanese

Authors
  1. Diego Pugliese
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  2. Nadia Giovanna Boetti
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  3. Davide Janner
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  4. Daniel Milanese
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Corresponding author

Correspondence to Diego Pugliese .

Editor information

Editors and Affiliations

  1. DISAT, Politecnico di Torino, Torino, Italy

    Francesco Baino

  2. DISAT, Politecnico di Torino, Torino, Italy

    Massimo Tomalino

  3. Department. of Natural-Mathematical Sciences, Turin Polytechnic University in Tashkent, Tashkent, Uzbekistan

    Dilshat Tulyaganov

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Pugliese, D., Boetti, N.G., Janner, D., Milanese, D. (2021). Optical Quality Resorbable Calcium-Phosphate Glasses for Biophotonic Applications. In: Baino, F., Tomalino, M., Tulyaganov, D. (eds) Ceramics, Glass and Glass-Ceramics. PoliTO Springer Series. Springer, Cham. https://doi.org/10.1007/978-3-030-85776-9_7

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