Abstract
The pharmacokinetic characteristics of fenfluramine are described, and the interaction effects of concomitant antiseizure medications on fenfluramine in terms of its pharmacokinetics and pharmacodynamics are highlighted.
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References
Summary of product characteristics: Fenfluramine (Fintepla). ZogenIix Int. Ltd. Last update 6 Jan 2021.
Boyd B, Smith S, Gammaitoni A, Galer BS, Farfel GM. A phase 1, randomized, open-label, single dose, 3 period crossover study to evaluate the drug-drug interaction between ZX008 (fenfluramine HCl oral solution) and a regimen of stiripentol, clobazam, and valproate in healthy subjects. Int J Clin Pharmaol Therapeut. 2019;57:11–9.
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Patsalos, P.N. (2022). Fenfluramine. In: Antiseizure Medication Interactions. Springer, Cham. https://doi.org/10.1007/978-3-030-82790-8_13
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DOI: https://doi.org/10.1007/978-3-030-82790-8_13
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Online ISBN: 978-3-030-82790-8
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