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Diagnostic Evaluation of Dementia

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Management of Patients with Dementia

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Abstract

Diagnosing dementia requires a multiprofessional approach using an array of investigative methods. A diagnosis of dementia and identification of the underlying cause, when possible, is essential for providing the necessary and appropriate treatment and care in a timely manner, including counseling. History taking from both patient and carer is a cornerstone of the diagnostic process. Within recent years, advances in biomarkers have pushed these to the forefront of the diagnostic work-up of patients with presumed dementia. These include advances within structural and functional imaging as well as cerebrospinal fluid (CSF)-based biomarkers. This has enabled biomarker-based diagnosis and more accurate identification of the underlying cause, especially with respect to neurodegenerative diseases. Besides a more accurate diagnosis, the present chapter will outline the diagnostic process and work-up of patients suspected of dementia and the utility of the tools available to the clinician.

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Author notes

  1. Amber Nous, Maxime Vande Vyver and Wietse Wiels contributed equally.

Authors and Affiliations

  1. Department of Neurology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium

    Amber Nous, Maxime Vande Vyver, Wietse Wiels & Sebastiaan Engelborghs

  2. Center for Neurosciences (C4N), Vrije Universiteit Brussel (VUB), Brussels, Belgium

    Amber Nous, Maxime Vande Vyver, Wietse Wiels & Sebastiaan Engelborghs

  3. Department of Biomedical Sciences, Reference Center for Biological Markers of Dementia (BIODEM), Institute Born-Bunge, University of Antwerp, Antwerp, Belgium

    Amber Nous, Maxime Vande Vyver & Sebastiaan Engelborghs

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  1. Amber Nous
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Correspondence to Sebastiaan Engelborghs .

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  1. Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

    Kristian Steen Frederiksen

  2. Danish Dementia Research Centre, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

    Gunhild Waldemar

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Nous, A., Vyver, M.V., Wiels, W., Engelborghs, S. (2021). Diagnostic Evaluation of Dementia. In: Frederiksen, K.S., Waldemar, G. (eds) Management of Patients with Dementia. Springer, Cham. https://doi.org/10.1007/978-3-030-77904-7_3

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