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Miniaturization in Separation Techniques

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Handbook of Bioanalytics

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Abstract

Minute bioanalytical samples often require special ways of their processing. Here, miniaturized separation techniques play an important role due to their numerous advantages like high separation efficiency, high sensitivity, and possibility of using not typical stationary and mobile phases. In this chapter, the basic information on capillary liquid chromatography and related techniques are presented. The system construction as well as methods of preparation of capillary columns is described. Capillary column packing and synthesis of monolithic stationary phases are also discussed. Examples of using capillary columns in sample preparation are also presented.

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Author information

Authors and Affiliations

  1. Centre for Modern Interdisciplinary Technologies, Nicolaus Copernicus University in Toruń, Toruń, Poland

    Michał Szumski

  2. Department of Environmental Chemistry and Bioanalytics, Nicolaus Copernicus University in Toruń, Toruń, Poland

    Bogusław Buszewski

Authors
  1. Michał Szumski
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  2. Bogusław Buszewski
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Correspondence to Bogusław Buszewski .

Editor information

Editors and Affiliations

  1. Environmental Chemistry and Bioanalytics, Nicolaus Copernicus University, Torun, Poland

    Bogusław Buszewski

  2. Faculty of Chemistry, Silesian University of Technology, Gliwice, Poland

    Irena Baranowska

Section Editor information

  1. Faculty of Chemistry, Applied Analytical Chemistry, Campus Essen, Essen, Germany

    Oliver J. Schmitz

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Szumski, M., Buszewski, B. (2022). Miniaturization in Separation Techniques. In: Buszewski, B., Baranowska, I. (eds) Handbook of Bioanalytics. Springer, Cham. https://doi.org/10.1007/978-3-030-63957-0_32-1

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  • DOI: https://doi.org/10.1007/978-3-030-63957-0_32-1

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  • Print ISBN: 978-3-030-63957-0

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