Abstract
Polymers are macromolecules, versatile in structure, constitution, and properties. They have wide range of applications in various fields such as biophysics, medicine, electronics, and other branches of science and technology. Among these polymers biomedical polymers are specially mentioned due to their less toxicity in vivo, easy to process and sterilized, better shelf life, light weight, and remarkable properties suited to the applications. The current research explores the various applications of biomedical polymers in the field of medicine. Applications are wide ranging with degradable polymers being used clinically as surgical sutures and implants. In order to fit functional demand, materials with desired physical, chemical, biological, biomechanical, and degradation properties must be selected.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Bremner I (1988) Manifestations of copper excess. Am J Clin Nutr 67:1069S–1073S
Buettner GR, Jurkiewicz BA (1996) Catalytic metals, ascorbate and free radicals: combinations to avoid. Radiat Res 145:532–541
Carmali S, Brocchini S (2014) Polyacetals. In: Natural and synthetic biomedical polymers, Natural and Synthetic Biomedical Polymers, pp 219–233
Cheadle WG (2006) Risk factors for surgical site infection. Surg Infect 7:S7–S11
Cometa S, Iatta R, Ricci MA, Ferretti C, de Giglio E (2013) Analytical characterization and antimicrobial properties of novel copper nanoparticles-loaded electrosynthesised hydrogel coatings. J Bioact Compat Polym 28:508–522
Curtis LT (2008) Prevention of hospital-acquired infections: review of non-pharmacological interventions. J Hosp Infect 69:204–219
Damm C, Munstedt H, Rosch A (2008) The antimicrobial efficacy of polyamide 6/silver-nano- and microcomposites. Mater Chem Phys 108:61–66
Damodaran VB, Joslin J, Reynolds MM (2012) Preparing biocompatible materials for non-permanent medical devices. Eur Pharm Rev 17(5):71–77
De Azeredo HMC (2009) Nanocomposites for food packaging applications. Food Res Int 42:1240–1253
De Giglio E, Cafagna D, Cometa S, Allegretta A, Pedico A, Giannossa LC, Sabbatini L, Mattioli-Belmonte M, Iatta R (2013) An innovative, easily fabricated, silver nanoparticle-based titanium implant coating: development and analytical characterization. Anal Bioanal Chem 405:805–816
Gaetke LM, Chow CK (2003) Copper toxicity, oxidative stress, and antioxidant nutrients. Toxicology 189:147–163
Galaev I, Mattiasson B (1999) Smart polymers and what they could do in biotechnology and medicine.Trends Biotechnol 17(8):335–40. https://doi.org/10.1016/s0167-7799(99)01345-1
Grass G, Rensing C, Solioz M (2011) Metallic copper as an antimicrobial surface. Appl Environ Microbiol 77:1541–1548
Gunawan C, Teoh WY, Marquis CP, Amal R (2011) Cytotoxic origin of copper(II) oxide nanoparticles: comparative studies with micron-sized particles, leachate, and metal salts. ACS Nano 5:7214–7225
Huang J, Murata H, Koepsel RR, Russell AJ, Matyjaszewski K (2007) Antibacterial polypropylene via surface-initiated atom transfer radical polymerization. Biomacromolecules 8:1396–1399
Jones DS, Djokic J, Gorman SP (2005) The resistance of polyvinylpyrrolidone-Iodine-poly (ε-caprolactone) blends to adherence of Escherichia coli. Biomaterials 26:2013–2020
Kenawy ER, Worley SD, Broughton R (2007) The chemistry and applications of antimicrobial polymers: a state-of-the-art review. Biomacromolecules 8:1359–1384
Kumar V, Jolivalt C, Pulpytel J, Jafari R, Arefi-Khonsari F (2013) Development of silver nanoparticle loaded antibacterial polymer mesh using plasma polymerization process. J Biomed Mater Res A 101:1121–1132
Lee SB, Koepsel RR, Morley SW, Matyjaszewski K, Sun Y, Russel AJ (2004) Permanent nonleaching antibacterial surfaces 1: synthesis by atom transfer radical polymerization. Biomacromolecules 5:877–882
Lemire JA, Harrison JJ, Turner RJ (2013) Antimicrobial activity of metals: mechanisms, molecular targets and applications. Nat Rev Microbiol 11:371–384
Liechty WB, Kryscio DR, Slaughter BV, Peppas NA (2010) Polymers for drug delivery systems. Annu Rev Chem Biomol Eng 1:149–173
Middleton JC, Tipton AJ (2000) Synthetic biodegradable polymers as orthopedic devices. Biomaterials 21(23):2335–2346
Patil NV (2006) Smart polymers are in the biotech future. Bio Process International. Fluid Mechanics and Transport Phenomena. https://doi.org/10.1002/aic.11032
Pehlivan H, Balkose D, Ulku S, Tihminlioglu F (2005) Characterization of pure and silver exchanged natural zeolite filled polypropylene composite films. Compos Sci Technol 65:2049–2058
Parsa MH, Nasher al ahkami S, Pishbin H, Kazemi M (2012) Investigating spring back phenomena in double curved sheet metals forming. Materials & Design 41:326–337
Pishbin F, Mouriño V, Gilchrist JB, McComb DW, Kreppel S, Salih V, Ryan MP, Boccaccini AR (2013) Single-step electrochemical deposition of antimicrobial orthopaedic coatings based on a bioactive glass/chitosan/nano-silver composite system. Acta Biomater 9:7469–7479
Prabhu S, Poulose EK (2012) Silver nanoparticles: mechanism of antimicrobial action, synthesis, medical applications, and toxicity effects. Int Nano Lett 32:2–10
Sastri VR (2010) Plastics in medical devices: properties, requirements, and applications, A volume in Plastics Design Library, PDL Handbook series
Sastri VS (2010) Plastic in medical devices: properties, requirements and applications. Elsevier, Burlington
Shleeva S, Tkac J, Christenson A, Ruzgas T, Yaropolov AI, Whittaker JW, Gorton L (2005) Direct electron transfer between copper-containing proteins and electrodes. Biosens Bioelectron 20:2517–2554
Sintubin L, de Windt W, Dick J, Mast J, van der Ha D, Verstraete W, Boon N (2009) Lactic acid bacteria as reducing and cap** agent for the fast and efficient production of silver nanoparticles. Appl Microbiol Biotechnol 84:741–749
Stohs SJ, Bagchi D (1985) Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med 18:321–336
Valko M, Morris H, Cronin MTD (2005) Metals, toxicity and oxidative stress. Curr Med Chem 12:1161–1208
Yu SY, Yoo SJ, Yang L, Zapata C, Srinivasan A, Hay BA, Baker NE (2002) A pathway of signals regulating effector and initiator caspases in the develo** Drosophila eye. Development 129(13):3269–3278
Yuan YL, Ai F, Zang XP (2004) Polyurethane vascular catheter surface grafted with zwitterionic sulfobetaine monomer activated by ozone. Colloid Surf B 35:1–5
Zhang W, Zhang YH, Ji JH, Zhao J, Yan Q, Chu PK (2006) Antimicrobial properties of copper plasma-modified polyethylene. Polymer 47:7441–7445
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Nature Switzerland AG
About this entry
Cite this entry
Premkumar, J., SonicaSree, K., Sudhakar, T. (2021). Polymers in Biomedical Use. In: Hussain, C.M., Thomas, S. (eds) Handbook of Polymer and Ceramic Nanotechnology. Springer, Cham. https://doi.org/10.1007/978-3-030-40513-7_74
Download citation
DOI: https://doi.org/10.1007/978-3-030-40513-7_74
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-40512-0
Online ISBN: 978-3-030-40513-7
eBook Packages: Chemistry and Materials ScienceReference Module Physical and Materials ScienceReference Module Chemistry, Materials and Physics