Abstract
The high cure rate, coupled with the young age of patients with germ cell tumors, makes the impact of treatment on reproductive function, fertility, and progeny outcome an important issue. The majority of studies mentioned assessing the long-term effects of testicular cancer treatment on fertility have used reproductive hormone levels and semen analysis of sperm quality as surrogate markers of fertility. These markers are relatively simple to obtain and analyze in large numbers. However the degree to which deficiencies in these surrogate markers compromise the ability to father a child is not clear. Long-term fertility assessments, including paternity achievement, need to continue to be reported as this provides important information for the counseling and management of men with germ cell tumors.
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Daugaard, G., McDonald, F., Carlsen, E., Huddart, R. (2011). Fertility Issues. In: Laguna, M., Albers, P., Bokemeyer, C., Richie, J. (eds) Cancer of the Testis. Springer, London. https://doi.org/10.1007/978-1-84800-370-5_21
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